The Effect of Hemispheric Synchronization on Intraoperative Analgesia

Ariane K. Lewis, Irene P. Osborn, Ram Roth

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

In this double-blinded randomized study, we sought to confirm that patients undergoing general anesthesia who were exposed to a hemispheric synchronization (Hemi-Sync) musical recording during surgery had a smaller analgesia requirement, as was suggested in a previous study. Bispectral index monitoring was used to adjust depth of hypnosis, and hemodynamic variables were used to determine analgesia administration. Consented patients underwent either laparoscopic bariatric or one-level lumbar disk surgery. After endotracheal intubation and application of headphones, baseline heart rate and arterial blood pressure were established. Isoflurane was titrated to maintain sedation on the basis of a target bispectral index range of 40-60, and 25-μg increments of fentanyl were administered in response to increases in heart rate and systolic arterial blood pressure. Bariatric patients who listened to Hemi-Sync required one-third less fentanyl than the control group (mean [SD]: 0.015 [0.01] vs 0.024 μg · kg-1 · min-1 [0.01]) (P = 0.009). It is interesting to note that lumbar patients in the experimental and control groups required similar amounts of fentanyl (0.012 [0.01] vs 0.015 μg · kg-1 · min-1 [0.01]). End-tidal isoflurane concentration was similar for Hemi-Sync and blank-tape patients (bariatric, 0.74% (0.14) vs 0.77% (0.21); lumbar, 0.36% [0.16] vs 0.39% [0.12]). The bariatric patients in this study demonstrated that Hemi-Sync may be an innovative intraoperative supplement to analgesia.

Original languageEnglish (US)
Pages (from-to)533-536
Number of pages4
JournalAnesthesia and Analgesia
Volume98
Issue number2
StatePublished - Feb 2004
Externally publishedYes

Fingerprint

Analgesia
Bariatrics
Fentanyl
Isoflurane
Arterial Pressure
Heart Rate
Control Groups
Intratracheal Intubation
Hypnosis
General Anesthesia
Hemodynamics

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

The Effect of Hemispheric Synchronization on Intraoperative Analgesia. / Lewis, Ariane K.; Osborn, Irene P.; Roth, Ram.

In: Anesthesia and Analgesia, Vol. 98, No. 2, 02.2004, p. 533-536.

Research output: Contribution to journalArticle

Lewis, Ariane K. ; Osborn, Irene P. ; Roth, Ram. / The Effect of Hemispheric Synchronization on Intraoperative Analgesia. In: Anesthesia and Analgesia. 2004 ; Vol. 98, No. 2. pp. 533-536.
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