The intestinal mucosal reaction to colchicine in guinea pigs as measured by sucrase, maltase, and gamma glutamyl transpeptidase activity is described. There is a significant fall in disaccharidase activity without alteration in the peptidase activity after colchicine administration. This suggests a specific response of the disaccharidase system rather than a generalized toxic mucosal effect of colchicine.
|Original language||English (US)|
|Number of pages||4|
|Journal||The American Journal of Digestive Diseases|
|State||Published - Mar 1 1970|
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