The ecology of tumor

Paraic A. Kenny, Celeste M. Nelson, Mina J. Bissell

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

No tumor is an island. Chemical and physical forces exerted by the diverse cellular populations that surround a tumor - its so-called microenvironment - shape development and progression. Manipulating these 'ecological' factors is increasingly attractive therapeutically, as Mina Bissell and colleagues discuss in the following pages. And just as the cellular neighborhood is diverse, tumors enriched in these environments comprise a variety of cell types. In this heterogeneous mix, increasing evidence points to so-called cancer stem cells as the root of malignancy. Irving Weissman and Michael Clarke discuss the implications for leukemias on page 35, and on page 37 Peter B. Dirks discusses cancer stem cells in the brain.

Original languageEnglish (US)
Pages (from-to)30-35
Number of pages6
JournalScientist
Volume20
Issue number4
StatePublished - Apr 2006
Externally publishedYes

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ecology
cancer
environmental factors
brain
evidence

ASJC Scopus subject areas

  • General
  • Library and Information Sciences

Cite this

Kenny, P. A., Nelson, C. M., & Bissell, M. J. (2006). The ecology of tumor. Scientist, 20(4), 30-35.

The ecology of tumor. / Kenny, Paraic A.; Nelson, Celeste M.; Bissell, Mina J.

In: Scientist, Vol. 20, No. 4, 04.2006, p. 30-35.

Research output: Contribution to journalArticle

Kenny, PA, Nelson, CM & Bissell, MJ 2006, 'The ecology of tumor', Scientist, vol. 20, no. 4, pp. 30-35.
Kenny PA, Nelson CM, Bissell MJ. The ecology of tumor. Scientist. 2006 Apr;20(4):30-35.
Kenny, Paraic A. ; Nelson, Celeste M. ; Bissell, Mina J. / The ecology of tumor. In: Scientist. 2006 ; Vol. 20, No. 4. pp. 30-35.
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