The Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS): An instrument for assessing obsessive-compulsive symptom dimensions

M. C. Rosario-Campos, E. C. Miguel, S. Quatrano, P. Chacon, Y. Ferrao, D. Findley, L. Katsovich, L. Scahill, R. A. King, S. R. Woody, D. Tolin, Eric Hollander, Y. Kano, J. F. Leckman

Research output: Contribution to journalArticle

259 Citations (Scopus)

Abstract

Obsessive-compulsive disorder (OCD) encompasses a broad range of symptoms representing multiple domains. This complex phenotype can be summarized using a few consistent and temporally stable symptom dimensions. The objective of this study was to assess the psychometric properties of the Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS). This scale measures the presence and severity of obsessive-compulsive (OC) symptoms within six distinct dimensions that combine thematically related obsessions and compulsions. The DY-BOCS includes portions to be used as a self-report instrument and portions to be used by expert raters, including global ratings of OC symptom severity and overall impairment. We assessed 137 patients with a Diagnostic and Statistical Manual-IV diagnosis of OCD, aged 6-69 years, from sites in the USA, Canada and Brazil. Estimates of the reliability and validity of both the expert and self-report versions of the DY-BOCS were calculated and stratified according to age (pediatric vs. adult subjects). The internal consistency of each of the six symptom dimensions and the global severity score were excellent. The inter-rater agreement was also excellent for all component scores. Self-report and expert ratings were highly intercorrelated. The global DY-BOCS score was highly correlated with the total Yale-Brown Obsessive-Compulsive Scale score (Pearson r = 0.82, P < 0.0001). Severity scores for individual symptom dimensions were largely independent of one another, only modestly correlated with the global ratings, and were also differentially related to ratings of depression, anxiety and tic severity. No major differences were observed when the results were stratified by age. These results indicate that the DY-BOCS is a reliable and valid instrument for assessing multiple aspects of OCD symptom severity in natural history, neuroimaging, treatment response and genetic studies when administered by expert clinicians or their highly trained staff.

Original languageEnglish (US)
Pages (from-to)495-504
Number of pages10
JournalMolecular Psychiatry
Volume11
Issue number5
DOIs
StatePublished - May 2006
Externally publishedYes

Fingerprint

Obsessive-Compulsive Disorder
Self Report
Obsessive Behavior
Tics
Natural History
Psychometrics
Reproducibility of Results
Neuroimaging
Canada
Brazil
Anxiety
Depression
Pediatrics
Phenotype
Therapeutics

Keywords

  • Obsessive-compulsive disorder
  • Obsessive-compulsive symptom dimensions
  • Phenotypic heterogeneity
  • Scale

ASJC Scopus subject areas

  • Molecular Biology
  • Psychiatry and Mental health

Cite this

Rosario-Campos, M. C., Miguel, E. C., Quatrano, S., Chacon, P., Ferrao, Y., Findley, D., ... Leckman, J. F. (2006). The Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS): An instrument for assessing obsessive-compulsive symptom dimensions. Molecular Psychiatry, 11(5), 495-504. https://doi.org/10.1038/sj.mp.4001798

The Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS) : An instrument for assessing obsessive-compulsive symptom dimensions. / Rosario-Campos, M. C.; Miguel, E. C.; Quatrano, S.; Chacon, P.; Ferrao, Y.; Findley, D.; Katsovich, L.; Scahill, L.; King, R. A.; Woody, S. R.; Tolin, D.; Hollander, Eric; Kano, Y.; Leckman, J. F.

In: Molecular Psychiatry, Vol. 11, No. 5, 05.2006, p. 495-504.

Research output: Contribution to journalArticle

Rosario-Campos, MC, Miguel, EC, Quatrano, S, Chacon, P, Ferrao, Y, Findley, D, Katsovich, L, Scahill, L, King, RA, Woody, SR, Tolin, D, Hollander, E, Kano, Y & Leckman, JF 2006, 'The Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS): An instrument for assessing obsessive-compulsive symptom dimensions', Molecular Psychiatry, vol. 11, no. 5, pp. 495-504. https://doi.org/10.1038/sj.mp.4001798
Rosario-Campos, M. C. ; Miguel, E. C. ; Quatrano, S. ; Chacon, P. ; Ferrao, Y. ; Findley, D. ; Katsovich, L. ; Scahill, L. ; King, R. A. ; Woody, S. R. ; Tolin, D. ; Hollander, Eric ; Kano, Y. ; Leckman, J. F. / The Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS) : An instrument for assessing obsessive-compulsive symptom dimensions. In: Molecular Psychiatry. 2006 ; Vol. 11, No. 5. pp. 495-504.
@article{1202cebe17f149d086c48186205ab782,
title = "The Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS): An instrument for assessing obsessive-compulsive symptom dimensions",
abstract = "Obsessive-compulsive disorder (OCD) encompasses a broad range of symptoms representing multiple domains. This complex phenotype can be summarized using a few consistent and temporally stable symptom dimensions. The objective of this study was to assess the psychometric properties of the Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS). This scale measures the presence and severity of obsessive-compulsive (OC) symptoms within six distinct dimensions that combine thematically related obsessions and compulsions. The DY-BOCS includes portions to be used as a self-report instrument and portions to be used by expert raters, including global ratings of OC symptom severity and overall impairment. We assessed 137 patients with a Diagnostic and Statistical Manual-IV diagnosis of OCD, aged 6-69 years, from sites in the USA, Canada and Brazil. Estimates of the reliability and validity of both the expert and self-report versions of the DY-BOCS were calculated and stratified according to age (pediatric vs. adult subjects). The internal consistency of each of the six symptom dimensions and the global severity score were excellent. The inter-rater agreement was also excellent for all component scores. Self-report and expert ratings were highly intercorrelated. The global DY-BOCS score was highly correlated with the total Yale-Brown Obsessive-Compulsive Scale score (Pearson r = 0.82, P < 0.0001). Severity scores for individual symptom dimensions were largely independent of one another, only modestly correlated with the global ratings, and were also differentially related to ratings of depression, anxiety and tic severity. No major differences were observed when the results were stratified by age. These results indicate that the DY-BOCS is a reliable and valid instrument for assessing multiple aspects of OCD symptom severity in natural history, neuroimaging, treatment response and genetic studies when administered by expert clinicians or their highly trained staff.",
keywords = "Obsessive-compulsive disorder, Obsessive-compulsive symptom dimensions, Phenotypic heterogeneity, Scale",
author = "Rosario-Campos, {M. C.} and Miguel, {E. C.} and S. Quatrano and P. Chacon and Y. Ferrao and D. Findley and L. Katsovich and L. Scahill and King, {R. A.} and Woody, {S. R.} and D. Tolin and Eric Hollander and Y. Kano and Leckman, {J. F.}",
year = "2006",
month = "5",
doi = "10.1038/sj.mp.4001798",
language = "English (US)",
volume = "11",
pages = "495--504",
journal = "Molecular Psychiatry",
issn = "1359-4184",
publisher = "Nature Publishing Group",
number = "5",

}

TY - JOUR

T1 - The Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS)

T2 - An instrument for assessing obsessive-compulsive symptom dimensions

AU - Rosario-Campos, M. C.

AU - Miguel, E. C.

AU - Quatrano, S.

AU - Chacon, P.

AU - Ferrao, Y.

AU - Findley, D.

AU - Katsovich, L.

AU - Scahill, L.

AU - King, R. A.

AU - Woody, S. R.

AU - Tolin, D.

AU - Hollander, Eric

AU - Kano, Y.

AU - Leckman, J. F.

PY - 2006/5

Y1 - 2006/5

N2 - Obsessive-compulsive disorder (OCD) encompasses a broad range of symptoms representing multiple domains. This complex phenotype can be summarized using a few consistent and temporally stable symptom dimensions. The objective of this study was to assess the psychometric properties of the Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS). This scale measures the presence and severity of obsessive-compulsive (OC) symptoms within six distinct dimensions that combine thematically related obsessions and compulsions. The DY-BOCS includes portions to be used as a self-report instrument and portions to be used by expert raters, including global ratings of OC symptom severity and overall impairment. We assessed 137 patients with a Diagnostic and Statistical Manual-IV diagnosis of OCD, aged 6-69 years, from sites in the USA, Canada and Brazil. Estimates of the reliability and validity of both the expert and self-report versions of the DY-BOCS were calculated and stratified according to age (pediatric vs. adult subjects). The internal consistency of each of the six symptom dimensions and the global severity score were excellent. The inter-rater agreement was also excellent for all component scores. Self-report and expert ratings were highly intercorrelated. The global DY-BOCS score was highly correlated with the total Yale-Brown Obsessive-Compulsive Scale score (Pearson r = 0.82, P < 0.0001). Severity scores for individual symptom dimensions were largely independent of one another, only modestly correlated with the global ratings, and were also differentially related to ratings of depression, anxiety and tic severity. No major differences were observed when the results were stratified by age. These results indicate that the DY-BOCS is a reliable and valid instrument for assessing multiple aspects of OCD symptom severity in natural history, neuroimaging, treatment response and genetic studies when administered by expert clinicians or their highly trained staff.

AB - Obsessive-compulsive disorder (OCD) encompasses a broad range of symptoms representing multiple domains. This complex phenotype can be summarized using a few consistent and temporally stable symptom dimensions. The objective of this study was to assess the psychometric properties of the Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS). This scale measures the presence and severity of obsessive-compulsive (OC) symptoms within six distinct dimensions that combine thematically related obsessions and compulsions. The DY-BOCS includes portions to be used as a self-report instrument and portions to be used by expert raters, including global ratings of OC symptom severity and overall impairment. We assessed 137 patients with a Diagnostic and Statistical Manual-IV diagnosis of OCD, aged 6-69 years, from sites in the USA, Canada and Brazil. Estimates of the reliability and validity of both the expert and self-report versions of the DY-BOCS were calculated and stratified according to age (pediatric vs. adult subjects). The internal consistency of each of the six symptom dimensions and the global severity score were excellent. The inter-rater agreement was also excellent for all component scores. Self-report and expert ratings were highly intercorrelated. The global DY-BOCS score was highly correlated with the total Yale-Brown Obsessive-Compulsive Scale score (Pearson r = 0.82, P < 0.0001). Severity scores for individual symptom dimensions were largely independent of one another, only modestly correlated with the global ratings, and were also differentially related to ratings of depression, anxiety and tic severity. No major differences were observed when the results were stratified by age. These results indicate that the DY-BOCS is a reliable and valid instrument for assessing multiple aspects of OCD symptom severity in natural history, neuroimaging, treatment response and genetic studies when administered by expert clinicians or their highly trained staff.

KW - Obsessive-compulsive disorder

KW - Obsessive-compulsive symptom dimensions

KW - Phenotypic heterogeneity

KW - Scale

UR - http://www.scopus.com/inward/record.url?scp=33646146234&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33646146234&partnerID=8YFLogxK

U2 - 10.1038/sj.mp.4001798

DO - 10.1038/sj.mp.4001798

M3 - Article

C2 - 16432526

AN - SCOPUS:33646146234

VL - 11

SP - 495

EP - 504

JO - Molecular Psychiatry

JF - Molecular Psychiatry

SN - 1359-4184

IS - 5

ER -