Abstract
Curtailed protein translation ensures stemness and multipotency in embryonic and adult tissue-specific stem cells. In this issue of Cell, a study led by Zhao and colleagues uncovered increased susceptibility of hematopoietic stem cells (HSC) to iron-dependent programmed necrotic cell death (ferroptosis) as a consequence of low protein synthesis.
Original language | English (US) |
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Pages (from-to) | 685-687 |
Number of pages | 3 |
Journal | Cell |
Volume | 186 |
Issue number | 4 |
DOIs |
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State | Published - Feb 16 2023 |
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology