Curtailed protein translation ensures stemness and multipotency in embryonic and adult tissue-specific stem cells. In this issue of Cell, a study led by Zhao and colleagues uncovered increased susceptibility of hematopoietic stem cells (HSC) to iron-dependent programmed necrotic cell death (ferroptosis) as a consequence of low protein synthesis.
|Original language||English (US)|
|Number of pages||3|
|State||Published - Feb 16 2023|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)