TY - JOUR
T1 - The cost and impact of compulsivity
T2 - A research perspective
AU - Hollander, Eric
AU - Doernberg, Ellen
AU - Shavitt, Roseli
AU - Waterman, Richard J.
AU - Soreni, Noam
AU - Veltman, Dick J.
AU - Sahakian, Barbara J.
AU - Fineberg, Naomi A.
N1 - Publisher Copyright:
© 2016 Elsevier B.V. and ECNP.
PY - 2016/5/1
Y1 - 2016/5/1
N2 - Compulsivity is the defining feature of various psychiatric disorders including Obsessive Compulsive Related Disorders (OCRDs), and other compulsive, impulsive, and addictive disorders. These disorders are disabling, chronic conditions with an early onset and high rates of comorbidity, misdiagnoses, and delay in treatment onset. Disorders of compulsivity are responsible for considerable socioeconomic burden to society. We review the costs and impacts of compulsivity. In order to facilitate earlier diagnosis and targeted treatments, we examine the overlapping mechanisms that underlie compulsivity. We reconceptualize psychiatric disorders based on core features of compulsivity, highlight challenges in harmonizing research in children and adults, describe newer research methodologies, and point to future directions that can impact the costs and impact of disorders of compulsivity.
AB - Compulsivity is the defining feature of various psychiatric disorders including Obsessive Compulsive Related Disorders (OCRDs), and other compulsive, impulsive, and addictive disorders. These disorders are disabling, chronic conditions with an early onset and high rates of comorbidity, misdiagnoses, and delay in treatment onset. Disorders of compulsivity are responsible for considerable socioeconomic burden to society. We review the costs and impacts of compulsivity. In order to facilitate earlier diagnosis and targeted treatments, we examine the overlapping mechanisms that underlie compulsivity. We reconceptualize psychiatric disorders based on core features of compulsivity, highlight challenges in harmonizing research in children and adults, describe newer research methodologies, and point to future directions that can impact the costs and impact of disorders of compulsivity.
KW - Compulsivity
KW - Cost
KW - Diagnosis
KW - OCD
KW - OCRDs
KW - Treatment
UR - http://www.scopus.com/inward/record.url?scp=84969724096&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84969724096&partnerID=8YFLogxK
U2 - 10.1016/j.euroneuro.2016.02.006
DO - 10.1016/j.euroneuro.2016.02.006
M3 - Article
C2 - 27235690
AN - SCOPUS:84969724096
SN - 0924-977X
VL - 26
SP - 800
EP - 809
JO - European Neuropsychopharmacology
JF - European Neuropsychopharmacology
IS - 5
ER -