The contribution of immunohistochemistry in the diagnosis of pediatric neoplastic lesions in the University of Puerto Rico, School of Medicine.

D. Negrón, M. S. Correa, R. Vélez-Rosario, Lillian Colon, C. Gonzalez-Keelan

Research output: Contribution to journalArticle

Abstract

Immunohistochemistry has revolutionized the field of diagnostic pathology in the past fifteen years. Since then, it has been increasingly used as an adjunct to morphological diagnosis. The purpose of this retrospective analysis is to examine the value of this technique in the diagnosis of pediatric neoplasias in our laboratory. Forty eight pediatric cases, collected from January 1998 until May 1999, were reviewed, and classified in one of four categories: confirmed the morphological diagnosis, provided the definite diagnosis from a list of probable diagnoses, contributed by excluding other entities, and non-contributory. Immunohistochemistry confirmed the morphological diagnosis in 29 cases (60.4%), provided the definite diagnosis from a list of probable diagnoses in 13 cases (27.1%), was contributory by exclusion of other entities in 2 cases (4.2%), and was non-contributory in 4 cases (8.3%). In this preliminary study, we conclude that immunohistochemistry is being used in our laboratory mostly as a confirmatory tool for the definitive diagnosis of the lesions and once more exalts the utility of this technology in the field of diagnostic pathology.

Original languageEnglish (US)
Pages (from-to)335-341
Number of pages7
JournalPuerto Rico Health Sciences Journal
Volume20
Issue number4
StatePublished - 2001
Externally publishedYes

Fingerprint

Puerto Rico
Immunohistochemistry
Medicine
Pediatrics
Pathology
Technology

Cite this

The contribution of immunohistochemistry in the diagnosis of pediatric neoplastic lesions in the University of Puerto Rico, School of Medicine. / Negrón, D.; Correa, M. S.; Vélez-Rosario, R.; Colon, Lillian; Gonzalez-Keelan, C.

In: Puerto Rico Health Sciences Journal, Vol. 20, No. 4, 2001, p. 335-341.

Research output: Contribution to journalArticle

@article{ab601d07abd442ddad06883eda3c969a,
title = "The contribution of immunohistochemistry in the diagnosis of pediatric neoplastic lesions in the University of Puerto Rico, School of Medicine.",
abstract = "Immunohistochemistry has revolutionized the field of diagnostic pathology in the past fifteen years. Since then, it has been increasingly used as an adjunct to morphological diagnosis. The purpose of this retrospective analysis is to examine the value of this technique in the diagnosis of pediatric neoplasias in our laboratory. Forty eight pediatric cases, collected from January 1998 until May 1999, were reviewed, and classified in one of four categories: confirmed the morphological diagnosis, provided the definite diagnosis from a list of probable diagnoses, contributed by excluding other entities, and non-contributory. Immunohistochemistry confirmed the morphological diagnosis in 29 cases (60.4{\%}), provided the definite diagnosis from a list of probable diagnoses in 13 cases (27.1{\%}), was contributory by exclusion of other entities in 2 cases (4.2{\%}), and was non-contributory in 4 cases (8.3{\%}). In this preliminary study, we conclude that immunohistochemistry is being used in our laboratory mostly as a confirmatory tool for the definitive diagnosis of the lesions and once more exalts the utility of this technology in the field of diagnostic pathology.",
author = "D. Negr{\'o}n and Correa, {M. S.} and R. V{\'e}lez-Rosario and Lillian Colon and C. Gonzalez-Keelan",
year = "2001",
language = "English (US)",
volume = "20",
pages = "335--341",
journal = "Puerto Rico Health Sciences Journal",
issn = "0738-0658",
publisher = "University of Puerto Rico Medical Sciences Campus",
number = "4",

}

TY - JOUR

T1 - The contribution of immunohistochemistry in the diagnosis of pediatric neoplastic lesions in the University of Puerto Rico, School of Medicine.

AU - Negrón, D.

AU - Correa, M. S.

AU - Vélez-Rosario, R.

AU - Colon, Lillian

AU - Gonzalez-Keelan, C.

PY - 2001

Y1 - 2001

N2 - Immunohistochemistry has revolutionized the field of diagnostic pathology in the past fifteen years. Since then, it has been increasingly used as an adjunct to morphological diagnosis. The purpose of this retrospective analysis is to examine the value of this technique in the diagnosis of pediatric neoplasias in our laboratory. Forty eight pediatric cases, collected from January 1998 until May 1999, were reviewed, and classified in one of four categories: confirmed the morphological diagnosis, provided the definite diagnosis from a list of probable diagnoses, contributed by excluding other entities, and non-contributory. Immunohistochemistry confirmed the morphological diagnosis in 29 cases (60.4%), provided the definite diagnosis from a list of probable diagnoses in 13 cases (27.1%), was contributory by exclusion of other entities in 2 cases (4.2%), and was non-contributory in 4 cases (8.3%). In this preliminary study, we conclude that immunohistochemistry is being used in our laboratory mostly as a confirmatory tool for the definitive diagnosis of the lesions and once more exalts the utility of this technology in the field of diagnostic pathology.

AB - Immunohistochemistry has revolutionized the field of diagnostic pathology in the past fifteen years. Since then, it has been increasingly used as an adjunct to morphological diagnosis. The purpose of this retrospective analysis is to examine the value of this technique in the diagnosis of pediatric neoplasias in our laboratory. Forty eight pediatric cases, collected from January 1998 until May 1999, were reviewed, and classified in one of four categories: confirmed the morphological diagnosis, provided the definite diagnosis from a list of probable diagnoses, contributed by excluding other entities, and non-contributory. Immunohistochemistry confirmed the morphological diagnosis in 29 cases (60.4%), provided the definite diagnosis from a list of probable diagnoses in 13 cases (27.1%), was contributory by exclusion of other entities in 2 cases (4.2%), and was non-contributory in 4 cases (8.3%). In this preliminary study, we conclude that immunohistochemistry is being used in our laboratory mostly as a confirmatory tool for the definitive diagnosis of the lesions and once more exalts the utility of this technology in the field of diagnostic pathology.

UR - http://www.scopus.com/inward/record.url?scp=0035750025&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035750025&partnerID=8YFLogxK

M3 - Article

VL - 20

SP - 335

EP - 341

JO - Puerto Rico Health Sciences Journal

JF - Puerto Rico Health Sciences Journal

SN - 0738-0658

IS - 4

ER -