The common acute lymphoblastic leukemia antigen gene maps to chromosomal region 3 (q21-q27)

P. E. Barker, M. A. Shipp, L. D'Adamio, E. L. Masteller, E. L. Reinherz

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Complementary DNA and genomic clones corresponding to the gene for the common acute lymphoblastic leukemia antigen (CALLA) were used to investigate the genetic structure and location of the CALLA locus. The gene, which encodes a 100-kDa type II transmembrane glycoprotein, appears to be a single copy locus of greater than 45 kb which is not rearranged in malignancies expressing cell surface CALLA. Cell hybrid analysis indicates that the CALLA-related DNA sequences are found on human chromosome 3. In situ hybridization studies reveal the regional location of the CALLA locus to be 3q21-27.

Original languageEnglish (US)
Pages (from-to)283-287
Number of pages5
JournalJournal of Immunology
Volume142
Issue number1
StatePublished - 1989
Externally publishedYes

Fingerprint

Neprilysin
Genes
Chromosomes, Human, Pair 3
Hybrid Cells
Genetic Structures
Human Chromosomes
Surface Antigens
In Situ Hybridization
Glycoproteins
Complementary DNA
Clone Cells
Neoplasms

ASJC Scopus subject areas

  • Immunology

Cite this

Barker, P. E., Shipp, M. A., D'Adamio, L., Masteller, E. L., & Reinherz, E. L. (1989). The common acute lymphoblastic leukemia antigen gene maps to chromosomal region 3 (q21-q27). Journal of Immunology, 142(1), 283-287.

The common acute lymphoblastic leukemia antigen gene maps to chromosomal region 3 (q21-q27). / Barker, P. E.; Shipp, M. A.; D'Adamio, L.; Masteller, E. L.; Reinherz, E. L.

In: Journal of Immunology, Vol. 142, No. 1, 1989, p. 283-287.

Research output: Contribution to journalArticle

Barker, PE, Shipp, MA, D'Adamio, L, Masteller, EL & Reinherz, EL 1989, 'The common acute lymphoblastic leukemia antigen gene maps to chromosomal region 3 (q21-q27)', Journal of Immunology, vol. 142, no. 1, pp. 283-287.
Barker PE, Shipp MA, D'Adamio L, Masteller EL, Reinherz EL. The common acute lymphoblastic leukemia antigen gene maps to chromosomal region 3 (q21-q27). Journal of Immunology. 1989;142(1):283-287.
Barker, P. E. ; Shipp, M. A. ; D'Adamio, L. ; Masteller, E. L. ; Reinherz, E. L. / The common acute lymphoblastic leukemia antigen gene maps to chromosomal region 3 (q21-q27). In: Journal of Immunology. 1989 ; Vol. 142, No. 1. pp. 283-287.
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