The CentriMag ventricular assist device in acute heart failure refractory to medical management

Berhane Worku, Sang Woo Pak, Danielle Van Patten, Brian Housman, Nir Uriel, Paolo Colombo, Ulrich Jorde, Hiroo Takayama, Yoshifumi Naka

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Background: The CentriMag ventricular assist device (VAD) has gained popularity in the last several years as rescue support for patients with decompensated heart failure. We have used the CentriMag VAD as a bridge to decision device. We describe our experience with device placement, use and outcomes. Methods: This is a retrospective study of all patients who underwent CentriMag placement at our institution from January 2007 to August 2009. Sixty-three patients had placement of a CentriMag device, with 43% (n = 27) of these being placed due to failure of medical management. These cases were the focus of our study. Results: Primary diagnoses were ischemic cardiomyopathy (n = 17), dilated cardiomyopathy (n = 7) or other (n = 3). Mean age was 47.1 (range 7 to 72) years. Prior to implant, 85% of patients were on intra-aortic balloon pump (IABP) support, 70% were on vasopressors, and 44% were on more than one inotrope. INTERMACS score was 1 in 67% of patients and 2 in 33% of patients. Six patients were bridged to a long-term device, 8 to transplantation and 10 to recovery. Eighty-nine percent (24 of 27) of patients survived to explant and 74% (20 of 27) survived to hospital discharge, with a 1-year survival of 68%. Thromboembolic complications occurred in 10 patients, including 6 strokes. Compared with patients who survived to discharge, those who died had a significantly higher body mass index (30.8 vs 24.1 kg/m2, p = 0.003). Survivors to discharge demonstrated significant improvements in hepatic and renal function over the course of device support while non-survivors did not. Conclusions: The CentriMag demonstrates promising results when used in patients with acute heart failure refractory to medical management.

Original languageEnglish (US)
Pages (from-to)611-617
Number of pages7
JournalJournal of Heart and Lung Transplantation
Volume31
Issue number6
DOIs
StatePublished - Jun 1 2012
Externally publishedYes

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Keywords

  • BIVAD
  • cardiogenic shock
  • heart failure
  • mechanical circulatory support
  • medical management of shock

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Transplantation

Cite this

Worku, B., Pak, S. W., Van Patten, D., Housman, B., Uriel, N., Colombo, P., Jorde, U., Takayama, H., & Naka, Y. (2012). The CentriMag ventricular assist device in acute heart failure refractory to medical management. Journal of Heart and Lung Transplantation, 31(6), 611-617. https://doi.org/10.1016/j.healun.2011.12.016