The central nervous system in a cast of neurolathyrism

Max Striefler, Dan F. Cohn, Asao Hirano, Elias Schujman

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

We examined the central nervous system of a 67-year-old man who showed symptoms of lathyrism after being imprisoned at age 35 and fed on a diet of chick peas, Lathyrus sativus. The most obvious changes were loss of axons and myelin in the pyramidal tract in the lumbar spinal cord. These alterations correlated with spastic paraparesis. Other changes at the same level were a mild degree of degeneration of anterior horn cells. Pallor of Goll's tracts and axonal swelling in Goll's nuclei were also observed. A few examples of senile plaques and neurofibrillary tangles were observed in Ammon's horn.

Original languageEnglish (US)
Pages (from-to)1176-1178
Number of pages3
JournalNeurology
Volume27
Issue number12
StatePublished - 1977

Fingerprint

Lathyrism
Spinal Cord
Central Nervous System
Lathyrus
Spastic Paraparesis
Anterior Horn Cells
Pallor
Pyramidal Tracts
Neurofibrillary Tangles
Peas
Amyloid Plaques
Myelin Sheath
Axons
Hippocampus
Diet

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Striefler, M., Cohn, D. F., Hirano, A., & Schujman, E. (1977). The central nervous system in a cast of neurolathyrism. Neurology, 27(12), 1176-1178.

The central nervous system in a cast of neurolathyrism. / Striefler, Max; Cohn, Dan F.; Hirano, Asao; Schujman, Elias.

In: Neurology, Vol. 27, No. 12, 1977, p. 1176-1178.

Research output: Contribution to journalArticle

Striefler, M, Cohn, DF, Hirano, A & Schujman, E 1977, 'The central nervous system in a cast of neurolathyrism', Neurology, vol. 27, no. 12, pp. 1176-1178.
Striefler M, Cohn DF, Hirano A, Schujman E. The central nervous system in a cast of neurolathyrism. Neurology. 1977;27(12):1176-1178.
Striefler, Max ; Cohn, Dan F. ; Hirano, Asao ; Schujman, Elias. / The central nervous system in a cast of neurolathyrism. In: Neurology. 1977 ; Vol. 27, No. 12. pp. 1176-1178.
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