The Catecholaminergic Neurotransmitter System in Methylmercury-Induced Neurotoxicity

Marcelo Farina, Michael Aschner, João B.T. da Rocha

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations

Abstract

Both dopamine and norepinephrine play major roles in critical neuronal pathways linked to motor function, cognition, emotion, memory, and endocrine modulation. Impairments in catecholaminergic neurotransmission occur in response to methylmercury (MeHg) exposure. This chapter will focus on the toxic effects of MeHg on the catecholaminergic system, emphasizing the neurological consequences resulting from MeHg exposure, as well as related mechanisms of neurotoxicity.

Original languageEnglish (US)
Title of host publicationEnvironmental Factors in Neurodegenerative Diseases
EditorsMichael Aschner, Lucio G. Costa, Lucio G. Costa
PublisherElsevier Inc.
Pages47-81
Number of pages35
ISBN (Print)9780128127643
DOIs
StatePublished - Jan 2017

Publication series

NameAdvances in Neurotoxicology
Volume1
ISSN (Electronic)2468-7480

Keywords

  • Catecholamines
  • Mercury
  • Neurodegeneration
  • Neurotransmitters

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Health, Toxicology and Mutagenesis

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