The association between peripheral artery and lumbar spine disease: A Single-center Study

David L. Ain, David P. Slovut, Ravi Kamath, Michael R. Jaff

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

BACKGROUND: While intermittent claudication is the hallmark of symptomatic peripheral artery disease, most patients with peripheral artery disease have atypical symptoms. The presence of lumbosacral spine disease, a common cause of nonvascular lower extremity pain, may confound the diagnosis of peripheral artery disease. The goal of this study was to quantify the prevalence of severe lumbar spine degenerative disease in patients referred for lower extremity arterial studies. METHODS: All patients over age 18 years referred for segmental limb pressures and pulse volume recordings at rest and following treadmill exercise testing at a tertiary medical center accredited vascular diagnostic laboratory, who also underwent magnetic resonance imaging or computed tomography of the lumbar spine within 6 months of the arterial studies, were included in the analysis. Frequencies of peripheral artery disease and lumbar spine degenerative disease were determined, and medical records were reviewed for cardiovascular risk factors and prior vascular and spinal interventions. RESULTS: One hundred seven subjects (63 men) with a mean age of 70 years (range 35-88 years) were included in the analysis. Lumbar spine disease was present in 81 (75.7%) of the patients referred for vascular testing. The percentage of lumbar spine disease was equivalent in both patients with exercise-induced deterioration in arterial pressure and in those with a physiologic response to exercise. Compared with patients with a normal response to exercise, patients with exercise-induced peripheral artery disease had a lower resting ankle-brachial index (mean 0.79 vs 1.09, P <.001), abnormal pulse volume recordings, and were less likely to use opiate analgesics and more likely to have undergone lower extremity revascularization. CONCLUSIONS: Severe lumbar spine degenerative disease is widely prevalent in patients referred for lower extremity arterial studies. Our findings may help explain the high prevalence of atypical limb symptoms among peripheral artery disease patients.

Original languageEnglish (US)
Pages (from-to)411-415
Number of pages5
JournalAmerican Journal of Medicine
Volume125
Issue number4
DOIs
StatePublished - Apr 2012

Fingerprint

Spine
Arteries
Peripheral Arterial Disease
Exercise
Lower Extremity
Blood Vessels
Opiate Alkaloids
Extremities
Ankle Brachial Index
Intermittent Claudication
Medical Records
Analgesics
Arterial Pressure
Tomography
Magnetic Resonance Imaging
Blood Pressure
Pain

Keywords

  • Claudication
  • Peripheral artery disease
  • Spinal stenosis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

The association between peripheral artery and lumbar spine disease : A Single-center Study. / Ain, David L.; Slovut, David P.; Kamath, Ravi; Jaff, Michael R.

In: American Journal of Medicine, Vol. 125, No. 4, 04.2012, p. 411-415.

Research output: Contribution to journalArticle

Ain, David L. ; Slovut, David P. ; Kamath, Ravi ; Jaff, Michael R. / The association between peripheral artery and lumbar spine disease : A Single-center Study. In: American Journal of Medicine. 2012 ; Vol. 125, No. 4. pp. 411-415.
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