The association between alcohol and breast cancer risk: Evidence from the combined analysis of six dietary case‐control studies

Geoffrey Howe, Thomas Rohan, Adriano Decarli, José Iscovich, John Kaldor, Klea Katsouyanni, Ettore Marubini, Anthony Miller, Elio Riboli, Paolo Toniolo, Dimitrios Trichopoulos

Research output: Contribution to journalArticle

80 Scopus citations

Abstract

Data from 1,575 cases and 1,974 controls enrolled in 6 previously conducted case‐control studies of diet and breast cancer have been analysed with respect to alcohol intake. There appears to be an absence of any association between consumption of up to 40 g of alcohol per day and risk of breast cancer, and a highly statistically significant and consistent elevated risk of breast cancer for drinkers of 40 g or more of alcohol per day, for whom the relative risk, as compared with that of non‐drinkers, is 1.69 (95% confidence interval 1.19 to 2.40). This association is not due to confounding by a number of diet‐related factors, including total calories, fat, fibre and vitamin C.

Original languageEnglish (US)
Pages (from-to)707-710
Number of pages4
JournalInternational Journal of Cancer
Volume47
Issue number5
DOIs
StatePublished - Mar 12 1991
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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    Howe, G., Rohan, T., Decarli, A., Iscovich, J., Kaldor, J., Katsouyanni, K., Marubini, E., Miller, A., Riboli, E., Toniolo, P., & Trichopoulos, D. (1991). The association between alcohol and breast cancer risk: Evidence from the combined analysis of six dietary case‐control studies. International Journal of Cancer, 47(5), 707-710. https://doi.org/10.1002/ijc.2910470514