The assessment and treatment of refractory anxiety

E. Hollander, L. J. Cohen

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Most patients with anxiety disorders can be effectively treated with the use of specific pharmacologic and psychological approaches. Nevertheless, some anxiety patients remain refractory to standard treatments. For these patients, reappraisal and a systematic approach can be helpful. A common problem in patients with 'treatment-resistant' anxiety is the use of inadequate doses or inadequate duration of medication treatment. Alternatively, the diagnosis may need to be reconsidered, and comorbid diagnoses carefully assessed. Comorbid psychiatric, medical, and neurologic conditions may complicate the treatment of anxiety or require additional specific treatments. Finally, alternative pharmacologic approaches for specific types of anxiety can yield successful outcomes.

Original languageEnglish (US)
Pages (from-to)27-31
Number of pages5
JournalJournal of Clinical Psychiatry
Issue number2 SUPPL.
StatePublished - Jan 1 1994
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health


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