The adrenal cortex in adreno leukodystrophy

J. M. Powers, H. H. Schaumburg

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

The adrenal glands from 9 patients with hereditary adreno leukodystrophy were studied. Unique changes were found in the zona fasciculata and reticularis in 8 of the cases. These changes consisted of ballooned cortical cells, many of which had a striated cytoplasm with macrovacuoles. This spectrum of change suggests that the evolution of adrenal atrophy in this disease is a primary adrenolytic process. An autoimmune process, previously proposed in this condition, now seems unlikely.

Original languageEnglish (US)
Pages (from-to)305-310
Number of pages6
JournalArchives of Pathology and Laboratory Medicine
Volume96
Issue number5
StatePublished - 1973

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Zona Reticularis
Zona Fasciculata
Adrenergic Antagonists
Adrenal Cortex
Adrenal Glands
Atrophy
Cytoplasm

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

Cite this

Powers, J. M., & Schaumburg, H. H. (1973). The adrenal cortex in adreno leukodystrophy. Archives of Pathology and Laboratory Medicine, 96(5), 305-310.

The adrenal cortex in adreno leukodystrophy. / Powers, J. M.; Schaumburg, H. H.

In: Archives of Pathology and Laboratory Medicine, Vol. 96, No. 5, 1973, p. 305-310.

Research output: Contribution to journalArticle

Powers, JM & Schaumburg, HH 1973, 'The adrenal cortex in adreno leukodystrophy', Archives of Pathology and Laboratory Medicine, vol. 96, no. 5, pp. 305-310.
Powers, J. M. ; Schaumburg, H. H. / The adrenal cortex in adreno leukodystrophy. In: Archives of Pathology and Laboratory Medicine. 1973 ; Vol. 96, No. 5. pp. 305-310.
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