Thallium-201 myocardial scintigraphy in patients with triple-vessel disease and ischemic exercise stress tests

J. Leppo, T. Yipintsoi, R. Blankstein, R. Bontemps, Leonard M. Freeman, L. Zohman, J. Scheuer

Research output: Contribution to journalArticle

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Abstract

Thirty patents with triple-vessel coronary artery disease proven by angiography, symptomatic angina and a positive ECG stress test were evaluated with thallium-zol ( 201T1) scintigraphy. Twenty patients also had aortocoronary saphenous vein bypass surgery; 15 of them had repeat noninvasive evaluation. Seventy percent of these patients showed ischemia by 201Tl scintigraphy, of which one-half returned to normal after surgery. Postoperative reversion of the ECG stress test together with 201Tl stress/reperfusion imaging correlated well with the completeness of surgical revascularization. We could not explain the prevalence (80%) of infarcts detected by 201Tl in this group, of which 76% could be anatomically correlated to epicardial scars. The positivity of infarcts by 201Tl exceeded that predicted by previous history of infarction, Q waves on resting ECG or ventriculographic akinesis. These observations suggest that 201Tl scintigraphy is a useful noninvasive tool in the follow-up and understanding of patients with coronary heart disease. These conclusions also support the concept that 201Tl stress imaging need not have the identical connotation as the ECG stress test.

Original languageEnglish (US)
Pages (from-to)714-721
Number of pages8
JournalCirculation
Volume59
Issue number4
StatePublished - 1979
Externally publishedYes

Fingerprint

Myocardial Perfusion Imaging
Thallium
Exercise Test
Electrocardiography
Radionuclide Imaging
Patents
Saphenous Vein
Infarction
Reperfusion
Cicatrix
Coronary Disease
Coronary Artery Disease
Angiography
Ischemia

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Leppo, J., Yipintsoi, T., Blankstein, R., Bontemps, R., Freeman, L. M., Zohman, L., & Scheuer, J. (1979). Thallium-201 myocardial scintigraphy in patients with triple-vessel disease and ischemic exercise stress tests. Circulation, 59(4), 714-721.

Thallium-201 myocardial scintigraphy in patients with triple-vessel disease and ischemic exercise stress tests. / Leppo, J.; Yipintsoi, T.; Blankstein, R.; Bontemps, R.; Freeman, Leonard M.; Zohman, L.; Scheuer, J.

In: Circulation, Vol. 59, No. 4, 1979, p. 714-721.

Research output: Contribution to journalArticle

Leppo, J, Yipintsoi, T, Blankstein, R, Bontemps, R, Freeman, LM, Zohman, L & Scheuer, J 1979, 'Thallium-201 myocardial scintigraphy in patients with triple-vessel disease and ischemic exercise stress tests', Circulation, vol. 59, no. 4, pp. 714-721.
Leppo, J. ; Yipintsoi, T. ; Blankstein, R. ; Bontemps, R. ; Freeman, Leonard M. ; Zohman, L. ; Scheuer, J. / Thallium-201 myocardial scintigraphy in patients with triple-vessel disease and ischemic exercise stress tests. In: Circulation. 1979 ; Vol. 59, No. 4. pp. 714-721.
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