Tension-type headache and migraine in multiple sclerosis

Ilya Kister, Ana B. Caminero, Joseph Herbert, Richard B. Lipton

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

We review the evidence for a link between multiple sclerosis (MS) and two of the most common primary headache disorders: tension-type headache and migraine. We argue that the association between migraine and MS is biologically plausible and is confirmed by most studies. We discuss possible explanations for the association. First, we consider the possibility that the association is spurious. Next, we consider unidirectional causal models in which one of the conditions increases the risk of the other. A bidirectional model would suggest that each disease predisposes to the other. Alternatively, genetic or environmental risk factors shared by each condition may account for the association between them. We also address the question of whether coexisting migraine or tension-type headache in a patient with MS affects the symptom profile, clinical course, and radiographic characteristics of MS.

Original languageEnglish (US)
Pages (from-to)441-448
Number of pages8
JournalCurrent Pain and Headache Reports
Volume14
Issue number6
DOIs
StatePublished - Dec 2010

Fingerprint

Tension-Type Headache
Migraine Disorders
Multiple Sclerosis
Primary Headache Disorders

Keywords

  • Comorbidity
  • Epidemiology
  • Magnetic resonance imaging
  • Migraine
  • Multiple sclerosis
  • Symptomatology
  • Tension-type headache

ASJC Scopus subject areas

  • Clinical Neurology
  • Anesthesiology and Pain Medicine

Cite this

Tension-type headache and migraine in multiple sclerosis. / Kister, Ilya; Caminero, Ana B.; Herbert, Joseph; Lipton, Richard B.

In: Current Pain and Headache Reports, Vol. 14, No. 6, 12.2010, p. 441-448.

Research output: Contribution to journalArticle

Kister, Ilya ; Caminero, Ana B. ; Herbert, Joseph ; Lipton, Richard B. / Tension-type headache and migraine in multiple sclerosis. In: Current Pain and Headache Reports. 2010 ; Vol. 14, No. 6. pp. 441-448.
@article{c5940dbaffb6469788236af0a094e286,
title = "Tension-type headache and migraine in multiple sclerosis",
abstract = "We review the evidence for a link between multiple sclerosis (MS) and two of the most common primary headache disorders: tension-type headache and migraine. We argue that the association between migraine and MS is biologically plausible and is confirmed by most studies. We discuss possible explanations for the association. First, we consider the possibility that the association is spurious. Next, we consider unidirectional causal models in which one of the conditions increases the risk of the other. A bidirectional model would suggest that each disease predisposes to the other. Alternatively, genetic or environmental risk factors shared by each condition may account for the association between them. We also address the question of whether coexisting migraine or tension-type headache in a patient with MS affects the symptom profile, clinical course, and radiographic characteristics of MS.",
keywords = "Comorbidity, Epidemiology, Magnetic resonance imaging, Migraine, Multiple sclerosis, Symptomatology, Tension-type headache",
author = "Ilya Kister and Caminero, {Ana B.} and Joseph Herbert and Lipton, {Richard B.}",
year = "2010",
month = "12",
doi = "10.1007/s11916-010-0143-5",
language = "English (US)",
volume = "14",
pages = "441--448",
journal = "Current Pain and Headache Reports",
issn = "1531-3433",
publisher = "Current Science, Inc.",
number = "6",

}

TY - JOUR

T1 - Tension-type headache and migraine in multiple sclerosis

AU - Kister, Ilya

AU - Caminero, Ana B.

AU - Herbert, Joseph

AU - Lipton, Richard B.

PY - 2010/12

Y1 - 2010/12

N2 - We review the evidence for a link between multiple sclerosis (MS) and two of the most common primary headache disorders: tension-type headache and migraine. We argue that the association between migraine and MS is biologically plausible and is confirmed by most studies. We discuss possible explanations for the association. First, we consider the possibility that the association is spurious. Next, we consider unidirectional causal models in which one of the conditions increases the risk of the other. A bidirectional model would suggest that each disease predisposes to the other. Alternatively, genetic or environmental risk factors shared by each condition may account for the association between them. We also address the question of whether coexisting migraine or tension-type headache in a patient with MS affects the symptom profile, clinical course, and radiographic characteristics of MS.

AB - We review the evidence for a link between multiple sclerosis (MS) and two of the most common primary headache disorders: tension-type headache and migraine. We argue that the association between migraine and MS is biologically plausible and is confirmed by most studies. We discuss possible explanations for the association. First, we consider the possibility that the association is spurious. Next, we consider unidirectional causal models in which one of the conditions increases the risk of the other. A bidirectional model would suggest that each disease predisposes to the other. Alternatively, genetic or environmental risk factors shared by each condition may account for the association between them. We also address the question of whether coexisting migraine or tension-type headache in a patient with MS affects the symptom profile, clinical course, and radiographic characteristics of MS.

KW - Comorbidity

KW - Epidemiology

KW - Magnetic resonance imaging

KW - Migraine

KW - Multiple sclerosis

KW - Symptomatology

KW - Tension-type headache

UR - http://www.scopus.com/inward/record.url?scp=78649907617&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78649907617&partnerID=8YFLogxK

U2 - 10.1007/s11916-010-0143-5

DO - 10.1007/s11916-010-0143-5

M3 - Article

C2 - 20848239

AN - SCOPUS:78649907617

VL - 14

SP - 441

EP - 448

JO - Current Pain and Headache Reports

JF - Current Pain and Headache Reports

SN - 1531-3433

IS - 6

ER -