Tendon healing: Repair and regeneration

Pramod B. Voleti, Mark R. Buckley, Louis J. Soslowsky

Research output: Contribution to journalReview article

115 Citations (Scopus)

Abstract

Injury and degeneration of tendon, the soft tissue that mechanically links muscle and bone, can cause substantial pain and loss of function. This review discusses the composition and function of healthy tendon and describes the structural, biological, and mechanical changes initiated during the process of tendon healing. Biochemical pathways activated during repair, experimental injury models, and parallels between tendon healing and tendon development are emphasized, and cutting-edge strategies for the enhancement of tendon healing are discussed.

Original languageEnglish (US)
Pages (from-to)47-71
Number of pages25
JournalAnnual Review of Biomedical Engineering
Volume14
DOIs
StatePublished - Aug 2012
Externally publishedYes

Fingerprint

Tendons
Regeneration
Repair
Tendon Injuries
Theoretical Models
Muscle
Bone
Bone and Bones
Pain
Muscles
Tissue
Wounds and Injuries
Chemical analysis

Keywords

  • Tendon
  • Tendon animal models
  • Tendon injury
  • Tendon mechanics
  • Tendon repair

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biomedical Engineering

Cite this

Tendon healing : Repair and regeneration. / Voleti, Pramod B.; Buckley, Mark R.; Soslowsky, Louis J.

In: Annual Review of Biomedical Engineering, Vol. 14, 08.2012, p. 47-71.

Research output: Contribution to journalReview article

Voleti, Pramod B. ; Buckley, Mark R. ; Soslowsky, Louis J. / Tendon healing : Repair and regeneration. In: Annual Review of Biomedical Engineering. 2012 ; Vol. 14. pp. 47-71.
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