Temperature-sensitive mutants of reovirus type 3: Studies on the synthesis of viral peptides

Bernard N. Fields, Reuven Laskov, Matthew D. Scharff

Research output: Contribution to journalArticle

37 Scopus citations

Abstract

The synthesis of the major reovirus peptides has been examined in cells infected with ts mutants containing lesions in five cistrons. Immunological precipitation has been used so that peptides made in small amounts could be detected. At the permissive temperature, the mutants did not significantly differ from the wild type. At nonpermissive temperatures, different mutants produced different amounts of viral peptides, but all of the major peptides were made in the mutants examined and the size of each of these peptides was the same as in the wild type.

Original languageEnglish (US)
Pages (from-to)209-215
Number of pages7
JournalVirology
Volume50
Issue number1
DOIs
StatePublished - Oct 1972

ASJC Scopus subject areas

  • Virology

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