Targeting the anterior superior iliac spine yields significantly longer bone marrow cores

Louis Reed, Shirin Attarian, Gopichand Pendurti, Aditi P. Singh, Anjali Budhathoki, Simon Abi-Aad, Urvi A. Shah, Salem Kim, Kimo Bachiashvili, Jee Young Moon, Mimi Kim, Tarek Elrafei, Karenza Alexis, Marianna Strakhan, Weijuan Li, Ellen Friedman

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Pathologists and haematologists generally agree that the length of the biopsy core is a good surrogate for the diagnostic quality of the bone marrow. Previous studies suggested that the angulation of the biopsy needle from the posterior superior iliac spine (PSIS) could influence the length of the biopsy cores, targeting the anterior superior iliac spine (ASIS) from the PSIS would yield longer specimens than the traditional angulation technique (TAT), where the biopsy needle is directed straight in, perpendicular to the plane of the back. Twenty five adult haematology patients were prospectively recruited by haematologists-in-Training (HITs), who were trained to target the ASIS using a lateral angulationtechnique (LAT). The mean length of biopsy cores was 16 mm and that was significantly longer (p=0.003) than a comparable group of bone marrow biopsies previously obtained by HITs using the TAT approach. These results support the LAT as a new standard of haematology practice. Trial registration number NCT 02524613

Original languageEnglish (US)
Pages (from-to)172-173
Number of pages2
JournalJournal of Clinical Pathology
Issue number2
StatePublished - Feb 1 2018


  • bone marrow
  • bone marrow trephines
  • hematopathology

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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