Abstract
Recently, we demonstrated that stimulator of interferon genes (STING) ligand cyclic di-guanylate (c-di-GMP) is an excellent adjuvant in cancer vaccination but also induces immunogenic tumor cell death. Combination of both pathways resulted in a nearly complete elimination of the metastases in a breast cancer model. This study is discussed below.
Original language | English (US) |
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Journal | OncoImmunology |
Volume | 4 |
Issue number | 12 |
DOIs | |
State | Published - Dec 2 2015 |
Keywords
- IL-12
- Listeria-Mage-b
- STING ligand
- c-di-GMP
- metastatic breast cancer
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Oncology