Targeting signal transduction pathways in hematopoietic disorders

Li Zhou; Amit Verma

doi:10.1007/978-0-387-85816-6_11

Targeting signal transduction pathways in hematopoietic disorders

Li Zhou, Amit Verma

Oncology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Hematopoiesis is the process during which pluripotent stem cells give rise to lineage committed progenitors that differentiate into mature erythroid, myeloid, and lymphoid cells. This is a finely regulated process that is required for optimal maintenance of peripheral blood counts. Alterations in hematopoiesis can lead to a variety of bone marrow failure syndromes and hematological malignancies. Treatment of these diseases requires a detailed study of pathogenic mechanisms that lead to hematopoietic failure.

Original language	English (US)
Title of host publication	Molecular Basis of Hematopoiesis
Publisher	Springer New York
Pages	231-252
Number of pages	22
ISBN (Print)	9780387858159
DOIs	https://doi.org/10.1007/978-0-387-85816-6_11
State	Published - 2009

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

Access to Document

10.1007/978-0-387-85816-6_11

Cite this

@inbook{3e03431e1ad846d58dda15548b301193,

title = "Targeting signal transduction pathways in hematopoietic disorders",

abstract = "Hematopoiesis is the process during which pluripotent stem cells give rise to lineage committed progenitors that differentiate into mature erythroid, myeloid, and lymphoid cells. This is a finely regulated process that is required for optimal maintenance of peripheral blood counts. Alterations in hematopoiesis can lead to a variety of bone marrow failure syndromes and hematological malignancies. Treatment of these diseases requires a detailed study of pathogenic mechanisms that lead to hematopoietic failure.",

author = "Li Zhou and Amit Verma",

year = "2009",

doi = "10.1007/978-0-387-85816-6_11",

language = "English (US)",

isbn = "9780387858159",

pages = "231--252",

booktitle = "Molecular Basis of Hematopoiesis",

publisher = "Springer New York",

}

TY - CHAP

T1 - Targeting signal transduction pathways in hematopoietic disorders

AU - Zhou, Li

AU - Verma, Amit

PY - 2009

Y1 - 2009

N2 - Hematopoiesis is the process during which pluripotent stem cells give rise to lineage committed progenitors that differentiate into mature erythroid, myeloid, and lymphoid cells. This is a finely regulated process that is required for optimal maintenance of peripheral blood counts. Alterations in hematopoiesis can lead to a variety of bone marrow failure syndromes and hematological malignancies. Treatment of these diseases requires a detailed study of pathogenic mechanisms that lead to hematopoietic failure.

AB - Hematopoiesis is the process during which pluripotent stem cells give rise to lineage committed progenitors that differentiate into mature erythroid, myeloid, and lymphoid cells. This is a finely regulated process that is required for optimal maintenance of peripheral blood counts. Alterations in hematopoiesis can lead to a variety of bone marrow failure syndromes and hematological malignancies. Treatment of these diseases requires a detailed study of pathogenic mechanisms that lead to hematopoietic failure.

UR - http://www.scopus.com/inward/record.url?scp=84900065347&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84900065347&partnerID=8YFLogxK

U2 - 10.1007/978-0-387-85816-6_11

DO - 10.1007/978-0-387-85816-6_11

M3 - Chapter

AN - SCOPUS:84900065347

SN - 9780387858159

SP - 231

EP - 252

BT - Molecular Basis of Hematopoiesis

PB - Springer New York

ER -

Targeting signal transduction pathways in hematopoietic disorders

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this