Targeting signal transduction pathways in hematopoietic disorders

Li Zhou, Amit Verma

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Hematopoiesis is the process during which pluripotent stem cells give rise to lineage committed progenitors that differentiate into mature erythroid, myeloid, and lymphoid cells. This is a finely regulated process that is required for optimal maintenance of peripheral blood counts. Alterations in hematopoiesis can lead to a variety of bone marrow failure syndromes and hematological malignancies. Treatment of these diseases requires a detailed study of pathogenic mechanisms that lead to hematopoietic failure.

Original languageEnglish (US)
Title of host publicationMolecular Basis of Hematopoiesis
PublisherSpringer New York
Pages231-252
Number of pages22
ISBN (Print)9780387858159
DOIs
Publication statusPublished - Dec 1 2009

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ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Zhou, L., & Verma, A. (2009). Targeting signal transduction pathways in hematopoietic disorders. In Molecular Basis of Hematopoiesis (pp. 231-252). Springer New York. https://doi.org/10.1007/978-0-387-85816-6_11