Abstract
Studies of two distinct human T-cell systems have provided the exciting finding that T cells are able to recognize non-peptide antigens: γδ T cells have been shown to recognize isopentenyl pyrophosphate and related structures and human CD1 has been shown to present microbial lipids and lipoglycans such as mycolic acids and lipoarabinomannan to T cells. T-cell responses to these non-peptide antigens should provide a strategic target for immunologic intervention in infectious disease.
Original language | English (US) |
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Pages (from-to) | 510-516 |
Number of pages | 7 |
Journal | Current Opinion in Immunology |
Volume | 8 |
Issue number | 4 |
DOIs | |
State | Published - Aug 1996 |
Externally published | Yes |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology