T-cell receptor isoforms and signal transduction

Shigeo Koyasu, Luciano D'Adamio, Linda K. Clayton, Ellis L. Reinherz

Research output: Contribution to journalArticle

6 Scopus citations


Recent cDNA and genomic cloning have identified CD3Tη as an alternatively spliced product of the same gene locus that encodes CD3ζ. Three distinct T-cell receptor isoforms have now been identified. A current view of the signal transduction function of these isoforms in thymocytes and T cells is discussed.

Original languageEnglish (US)
Pages (from-to)32-39
Number of pages8
JournalCurrent Opinion in Immunology
Issue number1
StatePublished - 1991

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Fingerprint Dive into the research topics of 'T-cell receptor isoforms and signal transduction'. Together they form a unique fingerprint.

  • Cite this

    Koyasu, S., D'Adamio, L., Clayton, L. K., & Reinherz, E. L. (1991). T-cell receptor isoforms and signal transduction. Current Opinion in Immunology, 3(1), 32-39. https://doi.org/10.1016/0952-7915(91)90073-A