T-cell receptor isoforms and signal transduction

Shigeo Koyasu, Luciano D'Adamio, Linda K. Clayton, Ellis L. Reinherz

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Recent cDNA and genomic cloning have identified CD3Tη as an alternatively spliced product of the same gene locus that encodes CD3ζ. Three distinct T-cell receptor isoforms have now been identified. A current view of the signal transduction function of these isoforms in thymocytes and T cells is discussed.

Original languageEnglish (US)
Pages (from-to)32-39
Number of pages8
JournalCurrent Opinion in Immunology
Volume3
Issue number1
DOIs
StatePublished - 1991
Externally publishedYes

Fingerprint

T-Cell Antigen Receptor
Signal Transduction
Protein Isoforms
Thymocytes
Organism Cloning
Complementary DNA
T-Lymphocytes
Genes

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

Cite this

Koyasu, S., D'Adamio, L., Clayton, L. K., & Reinherz, E. L. (1991). T-cell receptor isoforms and signal transduction. Current Opinion in Immunology, 3(1), 32-39. https://doi.org/10.1016/0952-7915(91)90073-A

T-cell receptor isoforms and signal transduction. / Koyasu, Shigeo; D'Adamio, Luciano; Clayton, Linda K.; Reinherz, Ellis L.

In: Current Opinion in Immunology, Vol. 3, No. 1, 1991, p. 32-39.

Research output: Contribution to journalArticle

Koyasu, S, D'Adamio, L, Clayton, LK & Reinherz, EL 1991, 'T-cell receptor isoforms and signal transduction', Current Opinion in Immunology, vol. 3, no. 1, pp. 32-39. https://doi.org/10.1016/0952-7915(91)90073-A
Koyasu, Shigeo ; D'Adamio, Luciano ; Clayton, Linda K. ; Reinherz, Ellis L. / T-cell receptor isoforms and signal transduction. In: Current Opinion in Immunology. 1991 ; Vol. 3, No. 1. pp. 32-39.
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