Systemic necrotizing vasculitis associated with childhood sarcoidosis

Terry Kwong, Elsa Valderrama, Carole Paley, Norman Todd Ilowite

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Childhood sarcoidosis is a rare disorder with protean manifestations. The case of a child with prolonged fever, hepatosplenomegaly, pancytopenia, and systemic necrotizing vasculitis manifesting as fever, rash and skin infarctions, digital pregangrene, and foot drop is reported. This is the first case of systemic necrotizing vasculitis reported in sarcoidosis. The fulminant course of the disease required treatment with intravenous pulsed cyclophosphamide and high doses of corticosteroids. The spectrum of vasculitis in childhood and adult sarcoidosis is reviewed.

Original languageEnglish (US)
Pages (from-to)388-395
Number of pages8
JournalSeminars in Arthritis and Rheumatism
Volume23
Issue number6
DOIs
StatePublished - 1994

Fingerprint

Systemic Vasculitis
Sarcoidosis
Fever
Pancytopenia
Vasculitis
Exanthema
Cyclophosphamide
Infarction
Foot
Adrenal Cortex Hormones
Therapeutics

Keywords

  • granulomatous disease
  • Sarcoidosis
  • vasculitis

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Orthopedics and Sports Medicine
  • Rheumatology

Cite this

Systemic necrotizing vasculitis associated with childhood sarcoidosis. / Kwong, Terry; Valderrama, Elsa; Paley, Carole; Ilowite, Norman Todd.

In: Seminars in Arthritis and Rheumatism, Vol. 23, No. 6, 1994, p. 388-395.

Research output: Contribution to journalArticle

Kwong, Terry ; Valderrama, Elsa ; Paley, Carole ; Ilowite, Norman Todd. / Systemic necrotizing vasculitis associated with childhood sarcoidosis. In: Seminars in Arthritis and Rheumatism. 1994 ; Vol. 23, No. 6. pp. 388-395.
@article{ecca7db2e99c4723b856f308a22513a9,
title = "Systemic necrotizing vasculitis associated with childhood sarcoidosis",
abstract = "Childhood sarcoidosis is a rare disorder with protean manifestations. The case of a child with prolonged fever, hepatosplenomegaly, pancytopenia, and systemic necrotizing vasculitis manifesting as fever, rash and skin infarctions, digital pregangrene, and foot drop is reported. This is the first case of systemic necrotizing vasculitis reported in sarcoidosis. The fulminant course of the disease required treatment with intravenous pulsed cyclophosphamide and high doses of corticosteroids. The spectrum of vasculitis in childhood and adult sarcoidosis is reviewed.",
keywords = "granulomatous disease, Sarcoidosis, vasculitis",
author = "Terry Kwong and Elsa Valderrama and Carole Paley and Ilowite, {Norman Todd}",
year = "1994",
doi = "10.1016/0049-0172(94)90089-2",
language = "English (US)",
volume = "23",
pages = "388--395",
journal = "Seminars in Arthritis and Rheumatism",
issn = "0049-0172",
publisher = "W.B. Saunders Ltd",
number = "6",

}

TY - JOUR

T1 - Systemic necrotizing vasculitis associated with childhood sarcoidosis

AU - Kwong, Terry

AU - Valderrama, Elsa

AU - Paley, Carole

AU - Ilowite, Norman Todd

PY - 1994

Y1 - 1994

N2 - Childhood sarcoidosis is a rare disorder with protean manifestations. The case of a child with prolonged fever, hepatosplenomegaly, pancytopenia, and systemic necrotizing vasculitis manifesting as fever, rash and skin infarctions, digital pregangrene, and foot drop is reported. This is the first case of systemic necrotizing vasculitis reported in sarcoidosis. The fulminant course of the disease required treatment with intravenous pulsed cyclophosphamide and high doses of corticosteroids. The spectrum of vasculitis in childhood and adult sarcoidosis is reviewed.

AB - Childhood sarcoidosis is a rare disorder with protean manifestations. The case of a child with prolonged fever, hepatosplenomegaly, pancytopenia, and systemic necrotizing vasculitis manifesting as fever, rash and skin infarctions, digital pregangrene, and foot drop is reported. This is the first case of systemic necrotizing vasculitis reported in sarcoidosis. The fulminant course of the disease required treatment with intravenous pulsed cyclophosphamide and high doses of corticosteroids. The spectrum of vasculitis in childhood and adult sarcoidosis is reviewed.

KW - granulomatous disease

KW - Sarcoidosis

KW - vasculitis

UR - http://www.scopus.com/inward/record.url?scp=0028292055&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028292055&partnerID=8YFLogxK

U2 - 10.1016/0049-0172(94)90089-2

DO - 10.1016/0049-0172(94)90089-2

M3 - Article

VL - 23

SP - 388

EP - 395

JO - Seminars in Arthritis and Rheumatism

JF - Seminars in Arthritis and Rheumatism

SN - 0049-0172

IS - 6

ER -