Abstract
OBJECTIVE: To delineate the clinical pattern of a cohort of male patients with systemic lupus erythematosus (SLE) and compare it with previously reported data. DESIGN: Retrospective review of hospital records. SUBJECTS: Male patients (n = 11) who were diagnosed with SLE and admitted to a 500-bed university hospital between 1990 and 1998. Eight of the men were African-American and three were Latino. The mean age was 36 years (range, 29-46). METHODS: Clinical and laboratory data were collected according to a well-established protocol. Imaging and invasive studies (including aspirations and biopsies) were also recorded. RESULTS: Nine of the patients (82%) had renal involvement, with five needing dialysis within a year of presentation. Five patients had neurologic involvement: two presented with psychosis and three with seizures. Eight patients had hematologic involvement, and seven had serosal and articular involvement. Cutaneous lesions (discoid lupus) were noted in only one patient. A majority of the patients were noncompliant and were lost to follow-up; therefore, ultimate outcome could not be clearly delineated. CONCLUSION: Renal, serosal, neurologic, articular, and hematologic involvement occurred frequently in our sample of male patients with SLE. The most striking finding was the high frequency of renal involvement with poor prognosis. A high index of suspicion for SLE in males may permit earlier diagnosis and may dictate the need for more aggressive therapy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 29-32 |
| Number of pages | 4 |
| Journal | The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women"s Health at Columbia |
| Volume | 3 |
| Issue number | 5 |
| State | Published - Jul 2000 |
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ASJC Scopus subject areas
- Physiology
- Pathology and Forensic Medicine
Cite this
Systemic lupus erythematosus in males : a retrospective study with a review of the literature. / Poduval, R. D.; Bananian, S.; Kumar, K. S.; Fomberstein, Barry J.
In: The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women"s Health at Columbia, Vol. 3, No. 5, 07.2000, p. 29-32.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Systemic lupus erythematosus in males
T2 - a retrospective study with a review of the literature.
AU - Poduval, R. D.
AU - Bananian, S.
AU - Kumar, K. S.
AU - Fomberstein, Barry J.
PY - 2000/7
Y1 - 2000/7
N2 - OBJECTIVE: To delineate the clinical pattern of a cohort of male patients with systemic lupus erythematosus (SLE) and compare it with previously reported data. DESIGN: Retrospective review of hospital records. SUBJECTS: Male patients (n = 11) who were diagnosed with SLE and admitted to a 500-bed university hospital between 1990 and 1998. Eight of the men were African-American and three were Latino. The mean age was 36 years (range, 29-46). METHODS: Clinical and laboratory data were collected according to a well-established protocol. Imaging and invasive studies (including aspirations and biopsies) were also recorded. RESULTS: Nine of the patients (82%) had renal involvement, with five needing dialysis within a year of presentation. Five patients had neurologic involvement: two presented with psychosis and three with seizures. Eight patients had hematologic involvement, and seven had serosal and articular involvement. Cutaneous lesions (discoid lupus) were noted in only one patient. A majority of the patients were noncompliant and were lost to follow-up; therefore, ultimate outcome could not be clearly delineated. CONCLUSION: Renal, serosal, neurologic, articular, and hematologic involvement occurred frequently in our sample of male patients with SLE. The most striking finding was the high frequency of renal involvement with poor prognosis. A high index of suspicion for SLE in males may permit earlier diagnosis and may dictate the need for more aggressive therapy.
AB - OBJECTIVE: To delineate the clinical pattern of a cohort of male patients with systemic lupus erythematosus (SLE) and compare it with previously reported data. DESIGN: Retrospective review of hospital records. SUBJECTS: Male patients (n = 11) who were diagnosed with SLE and admitted to a 500-bed university hospital between 1990 and 1998. Eight of the men were African-American and three were Latino. The mean age was 36 years (range, 29-46). METHODS: Clinical and laboratory data were collected according to a well-established protocol. Imaging and invasive studies (including aspirations and biopsies) were also recorded. RESULTS: Nine of the patients (82%) had renal involvement, with five needing dialysis within a year of presentation. Five patients had neurologic involvement: two presented with psychosis and three with seizures. Eight patients had hematologic involvement, and seven had serosal and articular involvement. Cutaneous lesions (discoid lupus) were noted in only one patient. A majority of the patients were noncompliant and were lost to follow-up; therefore, ultimate outcome could not be clearly delineated. CONCLUSION: Renal, serosal, neurologic, articular, and hematologic involvement occurred frequently in our sample of male patients with SLE. The most striking finding was the high frequency of renal involvement with poor prognosis. A high index of suspicion for SLE in males may permit earlier diagnosis and may dictate the need for more aggressive therapy.
UR - http://www.scopus.com/inward/record.url?scp=0034232555&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034232555&partnerID=8YFLogxK
M3 - Article
C2 - 11253253
AN - SCOPUS:0034232555
VL - 3
SP - 29
EP - 32
JO - Journal of Gender-Specific Medicine
JF - Journal of Gender-Specific Medicine
SN - 1523-7036
IS - 5
ER -