Systemic and local release of inflammatory cytokines regulates hepatobiliary excretion of 99mTc-mebrofenin

Brigid Joseph, Kuldeep K. Bhargava, Gene G. Tronco, Christopher J. Palestro, Sanjeev Gupta

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Imaging agents capable of providing cell compartment-specific information will facilitate studies of pathophysiological mechanisms, natural history of diseases, and therapeutic development. To demonstrate the effects of liver injury on the disposal of the organic anion mebrofenin, we performed animal studies.

Original languageEnglish (US)
Pages (from-to)336-344
Number of pages9
JournalNuclear Medicine Communications
Volume29
Issue number4
DOIs
StatePublished - Apr 2008

Keywords

  • Cytokine
  • Inflammation
  • Liver
  • Mebrofenin
  • Transport

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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