Systemic and local release of inflammatory cytokines regulates hepatobiliary excretion of 99mTc-mebrofenin

Brigid Joseph, Kuldeep K. Bhargava, Gene G. Tronco, Christopher J. Palestro, Sanjeev Gupta

Research output: Contribution to journalArticle

4 Scopus citations


Imaging agents capable of providing cell compartment-specific information will facilitate studies of pathophysiological mechanisms, natural history of diseases, and therapeutic development. To demonstrate the effects of liver injury on the disposal of the organic anion mebrofenin, we performed animal studies.

Original languageEnglish (US)
Pages (from-to)336-344
Number of pages9
JournalNuclear Medicine Communications
Issue number4
Publication statusPublished - Apr 2008



  • Cytokine
  • Inflammation
  • Liver
  • Mebrofenin
  • Transport

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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