Synapse-Specific Metaplasticity: To Be Silenced Is Not to Silence 2B

Benjamin D. Philpot, R. Suzanne Zukin

Research output: Contribution to journalShort survey

8 Scopus citations

Abstract

What happens to a single, presynaptically quiescent synapse among a population of active synapses? In this issue of Neuron, Ehlers and colleagues show that, far from being eliminated, these inactive synapses are primed for potentiation and incorporation into a new neural circuit through an upregulation of NR2B-containing NMDA receptors.

Original languageEnglish (US)
Pages (from-to)814-816
Number of pages3
JournalNeuron
Volume66
Issue number6
DOIs
Publication statusPublished - Jun 1 2010

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ASJC Scopus subject areas

  • Neuroscience(all)

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