Sutureless cataract incision closure using laser activated tissue glues

Alexander M. Eaton, Lawrence S. Bass, Steven K. Libutti, Hermann D. Schubert, Michael Treat

Research output: Contribution to journalConference article

11 Scopus citations

Abstract

With the advent of phacoemulsification and foldable intraocular lenses, there is renewed interest in sutureless cataract wound. We report the use of laser activated tissue glues for the closure of scleral tunnel cataract incisions. Two glue mixtures were tested in enucleated porcine eyes. Glue A was composed of hyaluronic acid, human albumin, and indocyanine green dye. Glue B contained hyaluronic acid, chondroitin sulfate, human albumin, and indocyanine green dye. A Spectra Physics diode laser (808 nm) with a power density of 7-11 watts/cm2 was used for glue activation. Wound bursting pressures, as determined by the presence of fluid at the wound margin, was significantly higher with both glue combinations than without the glue (P < 0.05). The mean wound bursting pressures for Glue A was 69.9 ± 17.1 mm Hg, and for Glue B was 42.9 ± 9.4 mm Hg. These results suggest that laser activated tissue glues may be an alternative to suture closure of scleral tunnel cataract incisions.

Original languageEnglish (US)
Pages (from-to)52-57
Number of pages6
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume1423
StatePublished - Jan 1 1991
EventProceedings of Ophthalmic Technologies - Los Angeles, CA, USA
Duration: Jan 21 1991Jan 22 1991

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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  • Cite this

    Eaton, A. M., Bass, L. S., Libutti, S. K., Schubert, H. D., & Treat, M. (1991). Sutureless cataract incision closure using laser activated tissue glues. Proceedings of SPIE - The International Society for Optical Engineering, 1423, 52-57.