Surface treatment with a new silanated derivative of tetraethylene glycol for biotechnological applications

P. S. Sit, D. Bolikal, J. H. Melman, M. D. Treiser, J. Kohn

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The design and synthesis of a silanated derivatives of tetraethylene glycol for biomedical applications were investigated. Silanated tetraethylene glycol (STEG) was synthesized by adding undecenyl moiety to TEG monoethyl ether under alkaline and air free conditions, resulting in the formation of an intermediate ether. Glass surfaces, pre-cleaned in a Nochromix solution, were modified by STEG. An immunofluorescence assay with slight modification was used to determine the relative amount of fibrinogen absorbed on modified and unmodified glass surfaces. Results show that silane is an effective agent for resisting protein adsorption.

Original languageEnglish (US)
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
StatePublished - Dec 1 2004
Externally publishedYes
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Publication series

NameTransactions - 7th World Biomaterials Congress

Other

OtherTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period5/17/045/21/04

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Sit, P. S., Bolikal, D., Melman, J. H., Treiser, M. D., & Kohn, J. (2004). Surface treatment with a new silanated derivative of tetraethylene glycol for biotechnological applications. In Transactions - 7th World Biomaterials Congress (Transactions - 7th World Biomaterials Congress).