Sudden onset blindness in sickle cell disease due to retinal artery occlusion

Robert I. Liem, Diane M. Calamaras, Manpreet S. Chhabra, Beatrice Files, Caterina P. Minniti, Alexis A. Thompson

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Central retinal artery occlusion (CRAO) is a rare and potentially devastating cause of acute blindness in sickle cell disease (SCD) that is unique compared to classic sickle retinopathy. Few details related to this complication in SCD are known, including its risk factors, pathogenesis, presentation, treatment and outcomes. We present three patients with SCD and retinal artery occlusion. The overall variability in clinical presentation, treatment and prognosis reported in the literature underscores the need for a greater understanding of these factors as they relate to this complication in SCD.

Original languageEnglish (US)
Pages (from-to)624-627
Number of pages4
JournalPediatric Blood and Cancer
Issue number3
StatePublished - Mar 2008
Externally publishedYes


  • Macular ischemia
  • Retinal artery occlusion
  • Sickle cell disease
  • Sudden blindness

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology


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