Successful pregnancy after transient ovarian failure following treatment of symptomatic leiomyomata

Peter Kovacs, John J. Stangel, Nanette F. Santoro, Harry J. Lieman

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Objective: To report a case of transient ovarian failure after treatment of symptomatic leiomyomata and review other iatrogenic causes of transient ovarian failure. Design: Case report and literature review. Setting: University-affiliated private practice. Patient(s): A 35-year-old woman with symptomatic leiomyomata. Intervention(s): Bilateral uterine artery embolization with subsequent abdominal myomectomy to treat unchanged regular heavy menstrual flow. Main Outcome Measure(s): Ovarian function. Result(s): Because medical therapy failed to control her menorrhagia, the patient proceeded with uterine artery embolization. She had persistent menorrhagia after bilateral uterine artery embolization and underwent exploratory laparotomy and myomectomy. After surgery, she had amenorrhea, hot flushes, and elevated FSH levels for 3 months. Ovarian function recovered after a short course of oral contraceptives, and the patient conceived without assistance. Conclusion(s): Several interventions can affect normal ovarian function and can lead to permanent or transient ovarian failure. Possible causes of transient ovarian failure are radioactive iodine treatment, radiation, chemotherapy, pelvic surgery, stress, and uterine artery embolization. Before these interventions are applied, the possibility of ovarian failure and available preventive measures should be discussed with the patient.

Original languageEnglish (US)
Pages (from-to)1292-1295
Number of pages4
JournalFertility and Sterility
Volume77
Issue number6
DOIs
StatePublished - 2002

Fingerprint

Uterine Artery Embolization
Leiomyoma
Treatment Failure
Uterine Myomectomy
Menorrhagia
Pregnancy
Private Practice
Amenorrhea
Oral Contraceptives
Iodine
Laparotomy
Outcome Assessment (Health Care)
Radiation
Drug Therapy
Therapeutics

Keywords

  • FSH
  • Myomectomy
  • Transient ovarian failure
  • Uterine artery embolization

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Successful pregnancy after transient ovarian failure following treatment of symptomatic leiomyomata. / Kovacs, Peter; Stangel, John J.; Santoro, Nanette F.; Lieman, Harry J.

In: Fertility and Sterility, Vol. 77, No. 6, 2002, p. 1292-1295.

Research output: Contribution to journalArticle

Kovacs, Peter ; Stangel, John J. ; Santoro, Nanette F. ; Lieman, Harry J. / Successful pregnancy after transient ovarian failure following treatment of symptomatic leiomyomata. In: Fertility and Sterility. 2002 ; Vol. 77, No. 6. pp. 1292-1295.
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