Subclavian artery pseudoaneurysm in type IV Ehlers-Danlos syndrome

P. I. Rossi, Larry A. Scher, S. G. Friedman, M. H. Hall, R. A. Boxer, M. G. Bialer

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

We report case of a subclavian artery pseudoaneurysm in a patient with type IV Ehlers-Danlos Syndrome. A 16-year-old-boy underwent successful repair of a subclavian artery pseudoaneurysm that occurred after a cervical hyperextension injury. Subsequent workup included skin biopsy and fibroblast culture, which were consistent with a diagnosis of type IV Ehlers-Danlos Syndrome. This condition is a dominantly inherited connective tissue disorder, which in this patient was found to be caused by a spontaneous point mutation in the COL3A1 gene that encodes the chains of type III procollagen. The clinical, genetic, and molecular characteristics of type IV Ehlers- Danlos Syndrome are briefly reviewed.

Original languageEnglish (US)
Pages (from-to)549-551
Number of pages3
JournalJournal of Vascular Surgery
Volume27
Issue number3
DOIs
StatePublished - 1998

Fingerprint

Ehlers-Danlos Syndrome
Subclavian Artery
False Aneurysm
Collagen Type III
Point Mutation
Connective Tissue
Molecular Biology
Fibroblasts
Biopsy
Skin
Wounds and Injuries
Genes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Rossi, P. I., Scher, L. A., Friedman, S. G., Hall, M. H., Boxer, R. A., & Bialer, M. G. (1998). Subclavian artery pseudoaneurysm in type IV Ehlers-Danlos syndrome. Journal of Vascular Surgery, 27(3), 549-551. https://doi.org/10.1016/S0741-5214(98)70331-3

Subclavian artery pseudoaneurysm in type IV Ehlers-Danlos syndrome. / Rossi, P. I.; Scher, Larry A.; Friedman, S. G.; Hall, M. H.; Boxer, R. A.; Bialer, M. G.

In: Journal of Vascular Surgery, Vol. 27, No. 3, 1998, p. 549-551.

Research output: Contribution to journalArticle

Rossi, P. I. ; Scher, Larry A. ; Friedman, S. G. ; Hall, M. H. ; Boxer, R. A. ; Bialer, M. G. / Subclavian artery pseudoaneurysm in type IV Ehlers-Danlos syndrome. In: Journal of Vascular Surgery. 1998 ; Vol. 27, No. 3. pp. 549-551.
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