Studies on the orientation of cyclic AMP dependent protein kinase in human erythrocyte membranes

C. S. Rubin, R. D. Rosenfeld, O. M. Rosen

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The topographic location of cyclic AMP dependent protein kinase was studied in preparations of permeable and sealed membranes derived from human erythrocytes. Both the catalytic and cyclic AMP binding components of protein kinase are localized on the inner, cytoplasmic, surface of the plasma membrane.

Original languageEnglish (US)
Pages (from-to)3735-3738
Number of pages4
JournalProceedings of the National Academy of Sciences of the United States of America
Issue number12 II
Publication statusPublished - Dec 1 1973


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