Studies on the nerve growth factor(NGF) from snake venom molecular heterogeneity

Ruth Hogue Angeletti

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

The nerve growth factor from the venoms of Crotalus adamanteus and Bothrops jararaca was analyzed by chromatography and gel filtration. The data obtained suggest that purified nerve growth factor aggregates and dissociates to form active molecules of various molecular weights. Evidence was found for the existence of an active nerve growth factor, possibly a fragment or a subunit, having a molecular weight of less than 5,000.

Original languageEnglish (US)
Pages (from-to)62-69
Number of pages8
JournalJournal of Chromatography A
Volume37
Issue numberC
DOIs
StatePublished - 1968

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

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