Studies on ribosomal RNA of Trypanosoma cruzi

H. Tanowitz, M. Wittner, M. Sveda, R. Soeiro

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Abstract

Ribosomal RNA of T. cruzi was studied by velocity sedimentation and radioactive labeling techniques. It was determined that the major T. cruzi ribosomal RNA species sediment at 26S and 21S, respectively. When cosedimented with mammalian rRNA species, the protozoan RNA could readily be distinguished. Precursor RNA of higher molecular weight was determined at approximately 31S, an estimated molecular weight of 2.5 x 106 daltons. These studies suggest that intracellular growth of T. cruzi can be monitored separately from its host cell.

Original languageEnglish (US)
Pages (from-to)1065-1069
Number of pages5
JournalJournal of Parasitology
Volume61
Issue number6
DOIs
Publication statusPublished - Jan 1 1975

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ASJC Scopus subject areas

  • Parasitology
  • Ecology, Evolution, Behavior and Systematics

Cite this

Tanowitz, H., Wittner, M., Sveda, M., & Soeiro, R. (1975). Studies on ribosomal RNA of Trypanosoma cruzi. Journal of Parasitology, 61(6), 1065-1069. https://doi.org/10.2307/3279377