Studies of maternal plasma prolactin and amniotic fluid prolactin: Effects of chlorpromazine and prostaglandin f2α

Ruth Freeman, Michael Lev-Gur, Robert M. Boyar, Harold Schulman

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We have studied the effect of chlorpromazine and PGF, on the blood and amniotic fluid levels of prolactin over a 1- hour period of time in women who were in the 14th— 20th week of gestation. Following intramuscular injection of chlorpromazine, maternal plasma prolactin rose 1.0- to 2.5-fold. No significant change was noted in maternal plasma after PGF, administration. Amniotic fluid prolactin declined by 6 to 56%. These changes may be dilutional.

Original languageEnglish (US)
Pages (from-to)282-286
Number of pages5
JournalObstetrics and gynecology
Issue number3
Publication statusPublished - Mar 1976


ASJC Scopus subject areas

  • Obstetrics and Gynecology

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