Studies of hepatic synthesis in vivo of plasma proteins, including orosomucoid, transferrin, α-antitrypsin, C8, and factor B

Chester A. Alper, Donald Raum, Zuheir L. Awdeh, Bruce H. Petersen, Paul D. Taylor, Thomas E. Starzl

Research output: Contribution to journalArticle

87 Scopus citations

Abstract

Serum protein types were determined in eight recipients and donors in cases of hepatic homotransplantation. A change from recipient type to donor type was observed for factor B, C8, orosomucoid, haptoglobin, transferrin, α1-antitrypsin, C3 and C6, but not for Gm and Inv immunoglobulin markers. The results indicate that all the proteins studied (except immunoglobulins) are produced primarily by the liver in vivo.

Original languageEnglish (US)
Pages (from-to)84-89
Number of pages6
JournalClinical Immunology and Immunopathology
Volume16
Issue number1
DOIs
StatePublished - May 1980

ASJC Scopus subject areas

  • Immunology and Allergy
  • Pathology and Forensic Medicine
  • Immunology

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