Studies of hepatic synthesis in vivo of plasma proteins, including orosomucoid, transferrin, α-antitrypsin, C8, and factor B

Chester A. Alper; Donald Raum; Zuheir L. Awdeh; Bruce H. Petersen; Paul D. Taylor; Thomas E. Starzl

doi:10.1016/0090-1229(80)90169-5

Studies of hepatic synthesis in vivo of plasma proteins, including orosomucoid, transferrin, α-antitrypsin, C8, and factor B

Chester A. Alper, Donald Raum, Zuheir L. Awdeh, Bruce H. Petersen, Paul D. Taylor, Thomas E. Starzl

Research output: Contribution to journal › Article › peer-review

99 Scopus citations

Abstract

Serum protein types were determined in eight recipients and donors in cases of hepatic homotransplantation. A change from recipient type to donor type was observed for factor B, C8, orosomucoid, haptoglobin, transferrin, α₁-antitrypsin, C3 and C6, but not for Gm and Inv immunoglobulin markers. The results indicate that all the proteins studied (except immunoglobulins) are produced primarily by the liver in vivo.

Original language	English (US)
Pages (from-to)	84-89
Number of pages	6
Journal	Clinical Immunology and Immunopathology
Volume	16
Issue number	1
DOIs	https://doi.org/10.1016/0090-1229(80)90169-5
State	Published - May 1980
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Pathology and Forensic Medicine
Immunology

Access to Document

10.1016/0090-1229(80)90169-5

Cite this

@article{7a23b1bf361d415d8d07637c2fbdd5fc,

title = "Studies of hepatic synthesis in vivo of plasma proteins, including orosomucoid, transferrin, α-antitrypsin, C8, and factor B",

abstract = "Serum protein types were determined in eight recipients and donors in cases of hepatic homotransplantation. A change from recipient type to donor type was observed for factor B, C8, orosomucoid, haptoglobin, transferrin, α1-antitrypsin, C3 and C6, but not for Gm and Inv immunoglobulin markers. The results indicate that all the proteins studied (except immunoglobulins) are produced primarily by the liver in vivo.",

author = "Alper, {Chester A.} and Donald Raum and Awdeh, {Zuheir L.} and Petersen, {Bruce H.} and Taylor, {Paul D.} and Starzl, {Thomas E.}",

year = "1980",

month = may,

doi = "10.1016/0090-1229(80)90169-5",

language = "English (US)",

volume = "16",

pages = "84--89",

journal = "Clinical Immunology and Immunopathology",

issn = "0090-1229",

publisher = "Academic Press Inc.",

number = "1",

}

TY - JOUR

T1 - Studies of hepatic synthesis in vivo of plasma proteins, including orosomucoid, transferrin, α-antitrypsin, C8, and factor B

AU - Alper, Chester A.

AU - Raum, Donald

AU - Awdeh, Zuheir L.

AU - Petersen, Bruce H.

AU - Taylor, Paul D.

AU - Starzl, Thomas E.

PY - 1980/5

Y1 - 1980/5

N2 - Serum protein types were determined in eight recipients and donors in cases of hepatic homotransplantation. A change from recipient type to donor type was observed for factor B, C8, orosomucoid, haptoglobin, transferrin, α1-antitrypsin, C3 and C6, but not for Gm and Inv immunoglobulin markers. The results indicate that all the proteins studied (except immunoglobulins) are produced primarily by the liver in vivo.

AB - Serum protein types were determined in eight recipients and donors in cases of hepatic homotransplantation. A change from recipient type to donor type was observed for factor B, C8, orosomucoid, haptoglobin, transferrin, α1-antitrypsin, C3 and C6, but not for Gm and Inv immunoglobulin markers. The results indicate that all the proteins studied (except immunoglobulins) are produced primarily by the liver in vivo.

UR - http://www.scopus.com/inward/record.url?scp=0018889401&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018889401&partnerID=8YFLogxK

U2 - 10.1016/0090-1229(80)90169-5

DO - 10.1016/0090-1229(80)90169-5

M3 - Article

C2 - 6769626

AN - SCOPUS:0018889401

SN - 0090-1229

VL - 16

SP - 84

EP - 89

JO - Clinical Immunology and Immunopathology

JF - Clinical Immunology and Immunopathology

IS - 1

ER -

Studies of hepatic synthesis in vivo of plasma proteins, including orosomucoid, transferrin, α-antitrypsin, C8, and factor B

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this