Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G

Evangelos Papadopoulos, Simon Jenni, Eihab Kabha, Khuloud J. Takrouri, Tingfang Yi, Nicola Salvi, Rafael E. Luna, Evripidis Gavathiotis, Poornachandran Mahalingam, Haribabu Arthanari, Ricard Rodriguez-Mias, Revital Yefidoff-Freedman, Bertal H. Aktas, Michael Chorev, Jose A. Halperin, Gerhard Wagner

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Medicine & Life Sciences