Structure and function of the somatosensory system

A neurotoxicological perspective

Joseph C. Arezzo, H. H. Schaumburg, P. S. Spencer

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The somatosensory system comprises those elements of the peripheral nervous system (PNS) and the central nervous system (CNS) subserving the modalities of touch, vibration, temperature, pain and kinesthesia. Specific modalities can be associated with unique peripheral receptors, peripheral axons of stereotyped diameter and specific central projection pathways. Several features of the somatosensory system render regions of it vulnerable to a wide variety of toxicants. The present report highlights these features and, furthermore, suggests that analysis of these regions is invaluable in studying the three most common varieties of toxic neuropathy: toxic distal axonopathy, toxic myelinopathy and toxic sensory neuronopathy.

Original languageEnglish (US)
Pages (from-to)23-30
Number of pages8
JournalEnvironmental Health Perspectives
VolumeVol. 44
StatePublished - 1982

Fingerprint

Poisons
nervous system
Neurology
vibration
Kinesthesis
Peripheral Nervous System
Touch
Vibration
Axons
Central Nervous System
temperature
Pain
Temperature
analysis

ASJC Scopus subject areas

  • Environmental Science(all)
  • Environmental Chemistry
  • Public Health, Environmental and Occupational Health

Cite this

Structure and function of the somatosensory system : A neurotoxicological perspective. / Arezzo, Joseph C.; Schaumburg, H. H.; Spencer, P. S.

In: Environmental Health Perspectives, Vol. Vol. 44, 1982, p. 23-30.

Research output: Contribution to journalArticle

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