Streptococcal toxic shock syndrome due to noninvasive pharyngitis

Edward K. Chapnick, Jeremy D. Gradon, Larry I. Lutwick, John Kim, Michael H. Levi, Michael H. Kim, Patrick M. Schlievert

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Serious infections due to group A β-hemolytic streptococcus (GABHS) have been reported with increasing frequency in recent years. We report a case of toxic shock syndrome (TSS) due to GABHS pharyngitis in an otherwise healthy 14-year-old boy. The organism was found to produce toxin A. To our knowledge, this is the second reported case of streptococcal TSS associated with the production of toxin A that is not associated with an invasive disease and the first case associated with a documented rise in the level of antibody to the streptococcal toxin itself. Clinicians must be especially vigilant for this entity in patients who have streptococcal pharyngitis because early recognition and institution of aggressive supportive therapy can be lifesaving.

Original languageEnglish (US)
Pages (from-to)1074-1077
Number of pages4
JournalClinical Infectious Diseases
Volume14
Issue number5
StatePublished - May 1992
Externally publishedYes

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Pharyngitis
Septic Shock
Streptococcus
Antibodies
Infection
Therapeutics

ASJC Scopus subject areas

  • Immunology

Cite this

Chapnick, E. K., Gradon, J. D., Lutwick, L. I., Kim, J., Levi, M. H., Kim, M. H., & Schlievert, P. M. (1992). Streptococcal toxic shock syndrome due to noninvasive pharyngitis. Clinical Infectious Diseases, 14(5), 1074-1077.

Streptococcal toxic shock syndrome due to noninvasive pharyngitis. / Chapnick, Edward K.; Gradon, Jeremy D.; Lutwick, Larry I.; Kim, John; Levi, Michael H.; Kim, Michael H.; Schlievert, Patrick M.

In: Clinical Infectious Diseases, Vol. 14, No. 5, 05.1992, p. 1074-1077.

Research output: Contribution to journalArticle

Chapnick, EK, Gradon, JD, Lutwick, LI, Kim, J, Levi, MH, Kim, MH & Schlievert, PM 1992, 'Streptococcal toxic shock syndrome due to noninvasive pharyngitis', Clinical Infectious Diseases, vol. 14, no. 5, pp. 1074-1077.
Chapnick EK, Gradon JD, Lutwick LI, Kim J, Levi MH, Kim MH et al. Streptococcal toxic shock syndrome due to noninvasive pharyngitis. Clinical Infectious Diseases. 1992 May;14(5):1074-1077.
Chapnick, Edward K. ; Gradon, Jeremy D. ; Lutwick, Larry I. ; Kim, John ; Levi, Michael H. ; Kim, Michael H. ; Schlievert, Patrick M. / Streptococcal toxic shock syndrome due to noninvasive pharyngitis. In: Clinical Infectious Diseases. 1992 ; Vol. 14, No. 5. pp. 1074-1077.
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