Streptococcal toxic shock syndrome due to noninvasive pharyngitis

Edward K. Chapnick, Jeremy D. Gradon, Larry I. Lutwick, John Kim, Michael Levi, Michael H. Kim, Patrick M. Schlievert

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Abstract

Serious infections due to group A β-hemolytic streptococcus (GABHS) have been reported with increasing frequency in recent years. We report a case of toxic shock syndrome (TSS) due to GABHS pharyngitis in an otherwise healthy 14-year-old boy. The organism was found to produce toxin A. To our knowledge, this is the second reported case of streptococcal TSS associated with the production of toxin A that is not associated with an invasive disease and the first case associated with a documented rise in the level of antibody to the streptococcal toxin itself. Clinicians must be especially vigilant for this entity in patients who have streptococcal pharyngitis because early recognition and institution of aggressive supportive therapy can be lifesaving.

Original languageEnglish (US)
Pages (from-to)1074-1077
Number of pages4
JournalClinical Infectious Diseases
Volume14
Issue number5
DOIs
Publication statusPublished - May 1 1992

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ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Chapnick, E. K., Gradon, J. D., Lutwick, L. I., Kim, J., Levi, M., Kim, M. H., & Schlievert, P. M. (1992). Streptococcal toxic shock syndrome due to noninvasive pharyngitis. Clinical Infectious Diseases, 14(5), 1074-1077. https://doi.org/10.1093/clinids/14.5.1074