Stem Cell Regeneration and Repair - Overview

Clement D. Marshall, Alessandra A. Moore, Michael T. Longaker, H. Peter Lorenz

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Mammalian skin holds a remarkable capacity to regenerate and repair itself in the face of continuous environmental exposures as well as frequent injuries. During normal skin homeostasis, a complex group of skin stem cells of different origins maintains skin in its healthy state. Following injury, these same stem cells are critical in the wound healing response that repairs the injury and forms new skin. Recent insights into the nature and identities of skin stem cells, gained through elegant and complex experiments, may allow for development of novel therapies that improve skin regeneration and reduce scarring by harnessing the capabilities of native skin stem cells.

Original languageEnglish (US)
Title of host publicationWound Healing
Subtitle of host publicationStem Cells Repair and Restorations, Basic and Clinical Aspects
PublisherWiley-Blackwell
Pages1-13
Number of pages13
ISBN (Electronic)9781119282518
ISBN (Print)9781119282488
DOIs
StatePublished - Jan 23 2018
Externally publishedYes

Keywords

  • Cutaneous injury
  • Regenerative medicine
  • Skin
  • Stem cell
  • Wound healing

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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