Statistical analysis of the distribution of the antibody levels to Mycobacterium bovis antigenes for bovine tuberculosis diagnostics

T. A. Redchuk, N. V. Korotkevich, Andrii Kaberniuk, E. S. Oliinyk, A. Yu Labyntsev, S. I. Romaniuk, D. V. Kolibo, V. A. Busol, S. V. Komisarenko

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The antibody responses to the recombinant analogs of Mycobacterium bovis antigens rMPB63 and rMPB83, as well as to tuberculin PPD, were determined in 96 bovine blood serum specimens. A statistical approach based on the approximation with multiple Gaussian curves with Levenberg-Marquardt algorithm was proposed for analysis of the distribution of antibody levels to the studied antigens. The results demonstrate that the recombinant MPB63 and MPB83 antigens along with the traditionally used PPD are appropriate for designing the test kits for diagnosing bovine tuberculosis at a herd level.

Original languageEnglish (US)
Pages (from-to)280-285
Number of pages6
JournalCytology and Genetics
Volume44
Issue number5
DOIs
StatePublished - Oct 2010
Externally publishedYes

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Statistical Distributions
Bovine Tuberculosis
Tuberculin
Mycobacterium bovis
Antigens
Antibodies
Antibody Formation
Serum

ASJC Scopus subject areas

  • Histology
  • Genetics
  • Genetics(clinical)

Cite this

Redchuk, T. A., Korotkevich, N. V., Kaberniuk, A., Oliinyk, E. S., Labyntsev, A. Y., Romaniuk, S. I., ... Komisarenko, S. V. (2010). Statistical analysis of the distribution of the antibody levels to Mycobacterium bovis antigenes for bovine tuberculosis diagnostics. Cytology and Genetics, 44(5), 280-285. https://doi.org/10.3103/S009545271005004X

Statistical analysis of the distribution of the antibody levels to Mycobacterium bovis antigenes for bovine tuberculosis diagnostics. / Redchuk, T. A.; Korotkevich, N. V.; Kaberniuk, Andrii; Oliinyk, E. S.; Labyntsev, A. Yu; Romaniuk, S. I.; Kolibo, D. V.; Busol, V. A.; Komisarenko, S. V.

In: Cytology and Genetics, Vol. 44, No. 5, 10.2010, p. 280-285.

Research output: Contribution to journalArticle

Redchuk, TA, Korotkevich, NV, Kaberniuk, A, Oliinyk, ES, Labyntsev, AY, Romaniuk, SI, Kolibo, DV, Busol, VA & Komisarenko, SV 2010, 'Statistical analysis of the distribution of the antibody levels to Mycobacterium bovis antigenes for bovine tuberculosis diagnostics', Cytology and Genetics, vol. 44, no. 5, pp. 280-285. https://doi.org/10.3103/S009545271005004X
Redchuk, T. A. ; Korotkevich, N. V. ; Kaberniuk, Andrii ; Oliinyk, E. S. ; Labyntsev, A. Yu ; Romaniuk, S. I. ; Kolibo, D. V. ; Busol, V. A. ; Komisarenko, S. V. / Statistical analysis of the distribution of the antibody levels to Mycobacterium bovis antigenes for bovine tuberculosis diagnostics. In: Cytology and Genetics. 2010 ; Vol. 44, No. 5. pp. 280-285.
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