Statistical analysis of the distribution of the antibody levels to Mycobacterium bovis antigenes for bovine tuberculosis diagnostics

T. A. Redchuk, N. V. Korotkevich, A. A. Kaberniuk, E. S. Oliinyk, A. Yu Labyntsev, S. I. Romaniuk, D. V. Kolibo, V. A. Busol, S. V. Komisarenko

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

The antibody responses to the recombinant analogs of Mycobacterium bovis antigens rMPB63 and rMPB83, as well as to tuberculin PPD, were determined in 96 bovine blood serum specimens. A statistical approach based on the approximation with multiple Gaussian curves with Levenberg-Marquardt algorithm was proposed for analysis of the distribution of antibody levels to the studied antigens. The results demonstrate that the recombinant MPB63 and MPB83 antigens along with the traditionally used PPD are appropriate for designing the test kits for diagnosing bovine tuberculosis at a herd level.

Original languageEnglish (US)
Pages (from-to)280-285
Number of pages6
JournalCytology and Genetics
Volume44
Issue number5
DOIs
StatePublished - Oct 1 2010

ASJC Scopus subject areas

  • Histology
  • Genetics
  • Genetics(clinical)

Fingerprint Dive into the research topics of 'Statistical analysis of the distribution of the antibody levels to Mycobacterium bovis antigenes for bovine tuberculosis diagnostics'. Together they form a unique fingerprint.

  • Cite this

    Redchuk, T. A., Korotkevich, N. V., Kaberniuk, A. A., Oliinyk, E. S., Labyntsev, A. Y., Romaniuk, S. I., Kolibo, D. V., Busol, V. A., & Komisarenko, S. V. (2010). Statistical analysis of the distribution of the antibody levels to Mycobacterium bovis antigenes for bovine tuberculosis diagnostics. Cytology and Genetics, 44(5), 280-285. https://doi.org/10.3103/S009545271005004X