Standardized measures in neuropathy

A. K. Asbury; D. Porte; J. Griffin; J. D. Ward; P. Raskin; D. Greene; A. A.F. Sima; P. C. Johnson; H. Schaumburg; J. W. Albers; J. Kimura; W. J. Litchy; A. J. Wilbourn; R. K. Olney; J. Arezzo; M. Rendell; J. Maurisson; J. Sosenko; A. Vinik

doi:10.2337/diacare.18.1.s59

Standardized measures in neuropathy

A. K. Asbury, D. Porte, J. Griffin, J. D. Ward, P. Raskin, D. Greene, A. A.F. Sima, P. C. Johnson, H. Schaumburg, J. W. Albers, J. Kimura, W. J. Litchy, A. J. Wilbourn, R. K. Olney, J. Arezzo, M. Rendell, J. Maurisson, J. Sosenko, A. Vinik

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

Several organ systems can be monitored by reliable longitudinal testing. These include: 1. Cardiovascular system: a. R-R variation b. Valsalva maneuver c. Postural blood pressure testing. 2. Sudomotor: a. Postganglionic function with QSART. 3. Eye: a. Dark-adapted pupil size after total parasympathetic blockade. Specific research projects may include other tests but these tests do not lend themselves easily for large, multicenter type of studies. The test listed above are noninvasive, quantitative, and are sufficiently standardized to allow longitudinal assessment in diabetic patients. Furthermore, these tests allow evaluation of at least three different organ systems. HAAF, an example of functional autonomic failure in diabetes, is best assessed by evaluation of the glycemic thresholds for epinephrine and pancreatic polypeptide secretion and hypoglycemic symptoms using a stepped hypoglycemic clamp protocol. The status of physiological defense against hyperinsulinemic hypoglycemia can be assessed with the insulin infusion test.

Original language	English (US)
Pages (from-to)	59-82
Number of pages	24
Journal	Diabetes care
Volume	18
Issue number	1 SUPPL.
DOIs	https://doi.org/10.2337/diacare.18.1.s59
State	Published - 1995
Externally published	Yes

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism
Advanced and Specialized Nursing

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2337/diacare.18.1.s59

Cite this

Asbury, A. K., Porte, D., Griffin, J., Ward, J. D., Raskin, P., Greene, D., Sima, A. A. F., Johnson, P. C., Schaumburg, H., Albers, J. W., Kimura, J., Litchy, W. J., Wilbourn, A. J., Olney, R. K., Arezzo, J., Rendell, M., Maurisson, J., Sosenko, J., & Vinik, A. (1995). Standardized measures in neuropathy. Diabetes care, 18(1 SUPPL.), 59-82. https://doi.org/10.2337/diacare.18.1.s59

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abstract = "Several organ systems can be monitored by reliable longitudinal testing. These include: 1. Cardiovascular system: a. R-R variation b. Valsalva maneuver c. Postural blood pressure testing. 2. Sudomotor: a. Postganglionic function with QSART. 3. Eye: a. Dark-adapted pupil size after total parasympathetic blockade. Specific research projects may include other tests but these tests do not lend themselves easily for large, multicenter type of studies. The test listed above are noninvasive, quantitative, and are sufficiently standardized to allow longitudinal assessment in diabetic patients. Furthermore, these tests allow evaluation of at least three different organ systems. HAAF, an example of functional autonomic failure in diabetes, is best assessed by evaluation of the glycemic thresholds for epinephrine and pancreatic polypeptide secretion and hypoglycemic symptoms using a stepped hypoglycemic clamp protocol. The status of physiological defense against hyperinsulinemic hypoglycemia can be assessed with the insulin infusion test.",

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year = "1995",

doi = "10.2337/diacare.18.1.s59",

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AU - Asbury, A. K.

AU - Porte, D.

AU - Griffin, J.

AU - Ward, J. D.

AU - Raskin, P.

AU - Greene, D.

AU - Sima, A. A.F.

AU - Johnson, P. C.

AU - Schaumburg, H.

AU - Albers, J. W.

AU - Kimura, J.

AU - Litchy, W. J.

AU - Wilbourn, A. J.

AU - Olney, R. K.

AU - Arezzo, J.

AU - Rendell, M.

AU - Maurisson, J.

AU - Sosenko, J.

AU - Vinik, A.

PY - 1995

Y1 - 1995

N2 - Several organ systems can be monitored by reliable longitudinal testing. These include: 1. Cardiovascular system: a. R-R variation b. Valsalva maneuver c. Postural blood pressure testing. 2. Sudomotor: a. Postganglionic function with QSART. 3. Eye: a. Dark-adapted pupil size after total parasympathetic blockade. Specific research projects may include other tests but these tests do not lend themselves easily for large, multicenter type of studies. The test listed above are noninvasive, quantitative, and are sufficiently standardized to allow longitudinal assessment in diabetic patients. Furthermore, these tests allow evaluation of at least three different organ systems. HAAF, an example of functional autonomic failure in diabetes, is best assessed by evaluation of the glycemic thresholds for epinephrine and pancreatic polypeptide secretion and hypoglycemic symptoms using a stepped hypoglycemic clamp protocol. The status of physiological defense against hyperinsulinemic hypoglycemia can be assessed with the insulin infusion test.

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Standardized measures in neuropathy

Abstract

ASJC Scopus subject areas

UN SDGs

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