Abstract
Three independent methods of measurement showed that cytoplasmic polyadenylated RNA from the differentiating myogenic cell line L8 consists of two main populations with regard to stability, one with a half-life of less than 4 h and the other with a half-life of 17-54 h. Similar results were obtained in the presence and absence of actinomycin D. During the fusion of mononucleated myoblasts into multinucleated fibers, there was an increase in both the steady-state pool of the more stable polyadenylated RNA and the proportion of stable polyadenylated RNA synthesized in pulse labelling.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 395-402 |
| Number of pages | 8 |
| Journal | European Journal of Biochemistry |
| Volume | 88 |
| Issue number | 2 |
| State | Published - 1978 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Biochemistry
Cite this
Stability of polyadenylated RNA in differentiating myogenic cells. / Singer, Robert H.; Kessler-Icekson, G.
In: European Journal of Biochemistry, Vol. 88, No. 2, 1978, p. 395-402.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Stability of polyadenylated RNA in differentiating myogenic cells
AU - Singer, Robert H.
AU - Kessler-Icekson, G.
PY - 1978
Y1 - 1978
N2 - Three independent methods of measurement showed that cytoplasmic polyadenylated RNA from the differentiating myogenic cell line L8 consists of two main populations with regard to stability, one with a half-life of less than 4 h and the other with a half-life of 17-54 h. Similar results were obtained in the presence and absence of actinomycin D. During the fusion of mononucleated myoblasts into multinucleated fibers, there was an increase in both the steady-state pool of the more stable polyadenylated RNA and the proportion of stable polyadenylated RNA synthesized in pulse labelling.
AB - Three independent methods of measurement showed that cytoplasmic polyadenylated RNA from the differentiating myogenic cell line L8 consists of two main populations with regard to stability, one with a half-life of less than 4 h and the other with a half-life of 17-54 h. Similar results were obtained in the presence and absence of actinomycin D. During the fusion of mononucleated myoblasts into multinucleated fibers, there was an increase in both the steady-state pool of the more stable polyadenylated RNA and the proportion of stable polyadenylated RNA synthesized in pulse labelling.
UR - http://www.scopus.com/inward/record.url?scp=0018104262&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0018104262&partnerID=8YFLogxK
M3 - Article
C2 - 689025
AN - SCOPUS:0018104262
VL - 88
SP - 395
EP - 402
JO - FEBS Journal
JF - FEBS Journal
SN - 1742-464X
IS - 2
ER -