Stability of end-of-life preferences: A systematic review of the evidence

Catherine L. Auriemma, Christina A. Nguyen, Rachel Bronheim, Saida Kent, Shrivatsa Nadiger, Dustin Pardo, Scott D. Halpern

Research output: Contribution to journalArticle

95 Citations (Scopus)

Abstract

IMPORTANCE: Policies and practices that promote advance care planning and advance directive completion implicitly assume that patients' choices for end-of-life (EOL) care are stable over time, even with changes in health status. OBJECTIVE: To systematically evaluate the evidence on the stability of EOL preferences over time and with changes in health status. EVIDENCE REVIEW: We searched for longitudinal studies of patients' preferences for EOL care in PubMed, EMBASE, and using citation review. Studies restricted to preferences regarding the place of care at the EOL were excluded. FINDINGS: A total of 296 articles were assessed for eligibility, and 59 met inclusion criteria. Twenty-four articles had sufficient data to extract or calculate the percentage of individuals with stable preferences or the percentage of total preferences that were stable over time. In 17 studies (71%) more than 70%of patients' preferences for EOL care were stable over time. Preference stability was generally greater among inpatients and seriously ill outpatients than among older adults without serious illnesses (P < .002). Patients with higher education and who had engaged in advance care planning had greater preference stability, and preferences to forgo therapies were generally more stable than preferences to receive therapies. Among 9 of the 24 studies (38%) assessing changes in health status, no consistent relationship with preference changes was identified. CONCLUSIONS AND RELEVANCE: Considerable variability among studies in the methods of preference assessment, the time between assessments, and the definitions of stability preclude meta-analytic estimates of the stability of patients' preferences and the factors influencing these preferences. Although more seriously ill patients and those who engage in advance care planning most commonly have stable preferences for future treatments, further research in real-world settings is needed to confirm the utility of advance care plans for future decision making.

Original languageEnglish (US)
Pages (from-to)1085-1092
Number of pages8
JournalJAMA Internal Medicine
Volume174
Issue number7
DOIs
StatePublished - 2014
Externally publishedYes

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Terminal Care
Advance Care Planning
Patient Preference
Health Status
Advance Directives
PubMed
Longitudinal Studies
Inpatients
Decision Making
Outpatients
Therapeutics
Education
Research

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Auriemma, C. L., Nguyen, C. A., Bronheim, R., Kent, S., Nadiger, S., Pardo, D., & Halpern, S. D. (2014). Stability of end-of-life preferences: A systematic review of the evidence. JAMA Internal Medicine, 174(7), 1085-1092. https://doi.org/10.1001/jamainternmed.2014.1183

Stability of end-of-life preferences : A systematic review of the evidence. / Auriemma, Catherine L.; Nguyen, Christina A.; Bronheim, Rachel; Kent, Saida; Nadiger, Shrivatsa; Pardo, Dustin; Halpern, Scott D.

In: JAMA Internal Medicine, Vol. 174, No. 7, 2014, p. 1085-1092.

Research output: Contribution to journalArticle

Auriemma, CL, Nguyen, CA, Bronheim, R, Kent, S, Nadiger, S, Pardo, D & Halpern, SD 2014, 'Stability of end-of-life preferences: A systematic review of the evidence', JAMA Internal Medicine, vol. 174, no. 7, pp. 1085-1092. https://doi.org/10.1001/jamainternmed.2014.1183
Auriemma, Catherine L. ; Nguyen, Christina A. ; Bronheim, Rachel ; Kent, Saida ; Nadiger, Shrivatsa ; Pardo, Dustin ; Halpern, Scott D. / Stability of end-of-life preferences : A systematic review of the evidence. In: JAMA Internal Medicine. 2014 ; Vol. 174, No. 7. pp. 1085-1092.
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