Stability and prognostic value of slug, SOX9, and SOX10 expression in breast cancers treated with neoadjuvant chemotherapy

Cosima Riemenschnitter, Ivett Teleki, Verena Tischler, Wenjun Guo, Zsuzsanna Varga

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Prognosis for breast cancer has improved continuously during the last decades but it is still one of the most frequent causes of tumor related death in women in the western world. Possible reasons of breast cancer mortality are tumor dormancy after treatment followed by local, regional or distant recurrence. Several factors as hormone receptors, HER2 status, proliferation fraction predicting outcome in preoperative setting were extensively examined in previous studies (Chen et al. 2013; Denkert et al. 2010; Lips et al. 2013; Payne et al. 2008; Teleki et al. 2013; van Nes et al. 2012; Varga et al. 2005; Yoshioka et al. 2013). The role of transcription factors (TF) in breast cancer prognosis has been the subject of some previous studies (Ablett et al. 2012; Cimino-Mathews et al. 2013; Giordano et al. 2012;.

Original languageEnglish (US)
Title of host publicationCancer Cell Signaling
Subtitle of host publicationTargeting Signaling Pathways Toward Therapeutic Approaches to Cancer
PublisherApple Academic Press
Pages289-306
Number of pages18
ISBN (Electronic)9781482299458
ISBN (Print)9781771880671
DOIs
StatePublished - Jan 1 2014

ASJC Scopus subject areas

  • General Medicine
  • General Biochemistry, Genetics and Molecular Biology

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