Squamous cell carcinoma of the scrotum

Squamous cell carcinoma of the scrotum still has a poor prognosis. However, patients with stage A1 disease have approximately a 75 per cent chance for long-term survival. Occupational-related and induced scrotal carcinomas are less frequent now because of better hygiene, protective clothing and awareness of the carcinogenity of industrial oils. The basic treatment for squamous cell carcinoma of the scrotum still depends upon wide local excision of the primary lesion. Before sentinel node biopsy or ilioinguinal lymphadenectomy patients should be treated with 4 to 6 weeks of antibiotics. Sentinel and superficial node biopsy should be done to rule out micrometastasis as well as to prove the need for ilioinguinal lymphadenectomy. Radiation therapy has little therapeutic benefit in the treatment of patients with squamous cell carcinoma of the scrotum. Bleomycin might be useful as adjuvant therapy for widespread ilioinguinal disease before attempted resection, although this has yet to be proved.