Spectroscopic determination of chelator content in antibody - Chelator conjugates: UV-Vis, fluorescence, and MALDI-TOF MS studies

E. Dadachova

Research output: Contribution to journalReview article

1 Scopus citations


Increasing use of monoclonal antibody-bifunctional chelator conjugates has created a need for quality control procedures providing relatively simple and reliable determination of the chelator-to-protein (C/P) ratio. Spectroscopic methods offer a valuable alternative to the use of radioactive isotapes for that purpose.

Original languageEnglish (US)
Pages (from-to)40-44
Number of pages5
Issue number11
StatePublished - Jan 1 2000


ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this