Spectroscopic determination of chelator content in antibody - Chelator conjugates: UV-Vis, fluorescence, and MALDI-TOF MS studies

E. Dadachova

Spectroscopic determination of chelator content in antibody - Chelator conjugates: UV-Vis, fluorescence, and MALDI-TOF MS studies

E. Dadachova

Radiology

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

Increasing use of monoclonal antibody-bifunctional chelator conjugates has created a need for quality control procedures providing relatively simple and reliable determination of the chelator-to-protein (C/P) ratio. Spectroscopic methods offer a valuable alternative to the use of radioactive isotapes for that purpose.

Original language	English (US)
Pages (from-to)	40-44
Number of pages	5
Journal	BioPharm
Volume	13
Issue number	11
State	Published - 2000

ASJC Scopus subject areas

Pharmaceutical Science

Cite this

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title = "Spectroscopic determination of chelator content in antibody - Chelator conjugates: UV-Vis, fluorescence, and MALDI-TOF MS studies",

abstract = "Increasing use of monoclonal antibody-bifunctional chelator conjugates has created a need for quality control procedures providing relatively simple and reliable determination of the chelator-to-protein (C/P) ratio. Spectroscopic methods offer a valuable alternative to the use of radioactive isotapes for that purpose.",

author = "E. Dadachova",

year = "2000",

language = "English (US)",

volume = "13",

pages = "40--44",

journal = "BioPharm",

issn = "1040-8304",

publisher = "Advanstar Communications",

number = "11",

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T1 - Spectroscopic determination of chelator content in antibody - Chelator conjugates

T2 - UV-Vis, fluorescence, and MALDI-TOF MS studies

AU - Dadachova, E.

PY - 2000

Y1 - 2000

N2 - Increasing use of monoclonal antibody-bifunctional chelator conjugates has created a need for quality control procedures providing relatively simple and reliable determination of the chelator-to-protein (C/P) ratio. Spectroscopic methods offer a valuable alternative to the use of radioactive isotapes for that purpose.

AB - Increasing use of monoclonal antibody-bifunctional chelator conjugates has created a need for quality control procedures providing relatively simple and reliable determination of the chelator-to-protein (C/P) ratio. Spectroscopic methods offer a valuable alternative to the use of radioactive isotapes for that purpose.

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M3 - Review article

AN - SCOPUS:0033729469

SN - 1040-8304

VL - 13

SP - 40

EP - 44

JO - BioPharm

JF - BioPharm

IS - 11

ER -

Spectroscopic determination of chelator content in antibody - Chelator conjugates: UV-Vis, fluorescence, and MALDI-TOF MS studies

Abstract

ASJC Scopus subject areas

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