Spatial and object working memory impairments in schizophrenia patients: A Bayesian item-response theory analysis

Michael J. Coleman, Samantha Cook, Steven Matthysse, John Barnard, Yungtai Lo, Deborah L. Levy, Donald B. Rubin, Philip S. Holzman

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Abstract

This study reports evidence that schizophrenia patients are significantly impaired in both spatial and object (shape) working memory. A 3-s delay between exposure and recall of targets was used and Bayesian item-response theory was applied to compensate for the tasks' differential difficulty while simultaneously taking account of missing data from participant attrition. Weaker evidence was found that in schizophrenia both domains are equally impaired on average, that spatial and object working memory appear to be more highly correlated with each other in the schizophrenia population than in the normal population, and that schizophrenia patients show greater variability in spatial than object working memory performance.

Original languageEnglish (US)
Pages (from-to)425-435
Number of pages11
JournalJournal of Abnormal Psychology
Volume111
Issue number3
DOIs
Publication statusPublished - Jan 1 2002

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ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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